• Genetic diversity and potential routes of transmission of Mycobacterium bovis in Mozambique 

      Machado, Adelina; Rito, Teresa; Ghebremichael, Solomon; Muhate, Nuelma; Maxhuza, Gabriel; Macuamule, Custodia; Moiane, Ivania; Macucule, Baltazar; Marranangumbe, Angelica Suzana; Baptista, Jorge; Manguele, Joaquim; Koivula, Tuija; Streicher, Elizabeth M.; Warren, Robin Mark; Kallenius, Gunilla; Van Helden, Paul; Correia-Neves, Margarida (Public Library of Science, 2018)
      Bovine tuberculosis is a zoonotic disease with largely unknown impact in Africa, with risk factors such as HIV and direct contact with animals or consumption of Mycobacterium bovis infected animal products. In order to ...
    • Geospatial distribution of Mycobacterium tuberculosis genotypes in Africa 

      Chihota, Violet N.; Niehaus, Antoinette; Streicher, Elizabeth M.; Wang, Xia; Sampson, Samantha L.; Mason, Peter; Kallenius, Gunilla; Mfinanga, Sayoki G.; Pillay, Marnomorney; Klopper, Marisa; Kasongo, Webster; Behr, Marcel A.; Van Pittius, Nicolaas C. Gey; Van Helden, Paul D.; Couvin, David; Rastogi, Nalin; Warren, Robin M. (Public Library of Science, 2018-08-01)
      Objective: To investigate the distribution of Mycobacterium tuberculosis genotypes across Africa. Methods: The SITVIT2 global repository and PUBMED were searched for spoligotype and published genotype data respectively, ...
    • Margarida Genetic diversity and potential routes of transmission of Mycobacterium bovis in Mozambique 

      Machado, Adelina; Rito, Teresa; Ghebremichael, Solomon; Muhate, Nuelma; Maxhuza, Gabriel; Macuamule, Custodia; Moiane, Ivania; Macucule, Baltazar; Marranangumbe, Angelica Suzana; Baptista, Jorge; Manguele, Joaquim; Koivula, Tuija; Streicher, Elizabeth M.; Warren, Robin Mark; Kallenius, Gunilla; Van Helden, Paul; Correia-Neves, Margarida (Public Library of Science, 2018)
      ENGLISH ABSTRACT: Bovine tuberculosis is a zoonotic disease with largely unknown impact in Africa, with risk factors such as HIV and direct contact with animals or consumption of Mycobacterium bovis infected animal ...
    • A sensitive urinary lipoarabinomannan test for tuberculosis 

      Hamasur, Beston; Bruchfeld, Judith; Van Helden, Paul; Kallenius, Gunilla; Svenson, Stefan (Public Library of Science, 2015)
      We have previously developed a diagnostic test for tuberculosis based on detection of mycobacterial lipoarabinomannan (LAM) in urine. The method depended on a laborious concentration step. We have now developed an easy ...
    • Translational research for tuberculosis elimination : priorities, challenges, and actions 

      Lienhardt, Christian; Lonnroth, Knut; Menzies, Dick; Balasegaram, Manica; Chakaya, Jeremiah; Cobelens, Frank; Cohn, Jennifer; Denkinger, Claudia M.; Evans, Thomas G.; Kallenius, Gunilla; Kaplan, Gilla; Kumar, Ajay M. V.; Matthiessen, Line; Mgone, Charles S.; Mizrahi, Valerie; Mukadi, Ya-diul; Nguyen, Viet Nhung; Nordstrom, Anders; Sizemore, Christine F.; Spigelman, Melvin; Squire, S. Bertel; Swaminathan, Soumya; Van Helden, Paul D.; Zumla, Alimuddin; Weyer, Karin; Weil, Diana; Raviglione, Mario (Public Library of Science, 2016)
      Summary Points: • The WHO End TB Strategy, endorsed by the World Health Assembly in May 2014, has the ambitious goal of ending the global tuberculosis (TB) epidemic by 2035, with targets of a 95% decline in deaths due ...