• The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria 

      Gey van Pittius, Nico C.; Gamieldien, Junaid; Hide, Winston; Brown, Gordon D.; Siezen, Roland J.; Beyers, Albert D. (BioMed Central, 2001-09)
      Background: The genome of Mycobacterium tuberculosis H37Rv has five copies of a cluster of genes known as the ESAT-6 loci. These clusters contain members of the CFP-10 (lhp) and ESAT-6 (esat-6) gene families (encoding ...
    • A new tool for prioritization of sequence variants from whole exome sequencing data 

      Glanzmann, Brigitte; Herbst, Hendri; Kinnear, Craig J.; Moller, Marlo; Gamieldien, Junaid; Bardien, Soraya (BioMed Central, 2016-07)
      Background: Whole exome sequencing (WES) has provided a means for researchers to gain access to a highly enriched subset of the human genome in which to search for variants that are likely to be pathogenic and possibly provide ...
    • Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans 

      Choudhury, Ananyo; Ramsay, Michele; Hazelhurst, Scott; Aron, Shaun; Bardien, Soraya; Botha, Gerrit; Chimusa, Emile R.; Christoffels, Alan; Gamieldien, Junaid; Sefid-Dashti, Mahjoubeh J.; Joubert, Fourie; Meintjes, Ayton; Mulder, Nicola; Ramesar, Raj; Rees, Jasper; Scholtz, Kathrine; Sengupta, Dhriti; Soodyall, Himla; Venter, Philip; Warnich, Louise; Pepper, Michael S. (Nature Research (part of Springer Nature), 2017)
      ENGLISH ABSTRACT: The Southern African Human Genome Programme is a national initiative that aspires to unlock the unique genetic character of southern African populations for a better understanding of human genetic ...