Skin conditions in epileptics
Date
1992
Authors
Swart E.
De Lochner V.J.
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Abstract
The prevalence of skin and mucous membrane conditions occurring in 173 epileptics between the ages of 6 and 19 years was compared with that of an age-matched group of 211 non-epileptics. The most frequently used anticonvulsants, singly or in combination, were carbamazepine in 54.9%, phenytoin in 47.8%, barbiturates in 36.6% and ethosuximide in 11.2% of epileptics. The most frequent combination was phenytoin and carbamazepine in 14% of the males and 18.4% of the females. An increased prevalence of acne was found in epileptic females; 80.3% compared to 30.2% in non-epileptic females. Hirsutism vas found in 43.9% of the female epileptics compared to 7.5% of the non-epileptic females. Of interest was the finding of punctate and linear scars on the dorsum of the hands of 27.7% epileptics compared to 3.8% non-epileptics. Both ephilides and naevocellular naevi occurred in 12.7% of the epileptics compared to 29.4% and 52.1% respectively of the non-epileptics. Leukonychia was also found more frequently in epileptics than in non-epileptics; 52% and 28.9% respectively.
Description
Keywords
anticonvulsive agent, barbituric acid derivative, carbamazepine, ethosuximide, phenytoin, adolescent, adult, article, child, epilepsy, female, human, major clinical study, male, oral drug administration, priority journal, skin disease, Adolescent, Adult, Anticonvulsants, Child, Drug Eruptions, Epilepsy, Tonic-Clonic, Female, Human, Male, Skin Diseases
Citation
Clinical and Experimental Dermatology
17
3
17
3