Homocysteine in vascular disease: An emerging clinical perspective
Date
2006
Authors
Jacobs P.
Wood L.
Bick R.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Traditionally, arterial and venous thrombo-embolism has been attributed to pathophysiological lesions in the vessel wall, or altered blood contents or flow through the lumen. Logically these fall into the category of a high-shear system, as opposed to the rather different circumstances in slowly moving columns of blood. The re-evaluation of this belief has been prompted by acknowledgement that there is currently a shift in emphasis. Recently we have recognised a common central factor in the internal dysfunction of the vessel that precedes and so initiates thrombocyte adhesion.
Description
Keywords
folic acid, homocysteine, blood vessel wall, clinical practice, clinical trial, coronary artery blood flow, human, pathophysiology, review, screening test, thrombocyte adhesion, thromboembolism, unspecified side effect, vascular disease, Animals, Atherosclerosis, Endothelium, Vascular, Genetic Predisposition to Disease, Homocysteine, Humans, Thrombophilia, Vascular Diseases
Citation
Cardiovascular Journal of South Africa
17
3
17
3