Homocysteine in vascular disease: An emerging clinical perspective

Jacobs P. ; Wood L. ; Bick R. (2006)

Review

Traditionally, arterial and venous thrombo-embolism has been attributed to pathophysiological lesions in the vessel wall, or altered blood contents or flow through the lumen. Logically these fall into the category of a high-shear system, as opposed to the rather different circumstances in slowly moving columns of blood. The re-evaluation of this belief has been prompted by acknowledgement that there is currently a shift in emphasis. Recently we have recognised a common central factor in the internal dysfunction of the vessel that precedes and so initiates thrombocyte adhesion.

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/13533
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