Management of Kaposi's sarcoma in resource-limited settings in the era of HAART

Lynen L. ; Zolfo M. ; Huyst V. ; Louis F. ; Barnardt P. ; de Velde A. ; De Schacht C. ; Colebunders R. (2005)


The introduction of highly active antiretroviral therapy (HAART) has changed the natural history of AIDS-associated Kaposi's sarcoma (KS). Although the use of HAART remains limited in low-resource settings, there are global initiatives to make these drugs available to several millions of HIV-infected persons. While there are multiple reports of KS regression during HAART with or without chemotherapy, there is little documentation on KS management in resource-limited settings. In this paper we review current KS treatments available worldwide and discuss the implications of the increased access to antiretrovirals for KS treatment strategies in resource-limited settings.

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