Complete genome sequencing of a non-syncytium-inducing HIV type 1 subtype D strain from Cape Town, South Africa
Date
2007
Authors
Jacobs G.B.
Loxton A.G.
Laten A.
Engelbrecht S.
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Journal ISSN
Volume Title
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Abstract
The fast growing HIV-1 epidemic in South Africa is mainly caused by HIV-1 group M subtype C, spreading via heterosexual transmission. In South Africa HIV-1 subtype B and D viruses were responsible for the initial epidemic during the 1980s, primarily in the homosexual population. This study describes the full-length PCR amplification and sequencing of an HIV-1 subtype D strain recovered from plasma from a sample taken during 1990. This is only the second full-length non-syncytium-inducing (NSI) subtype D strain described. Although restricted, the subtype D strain is still being detected in the South African population. © 2007 Mary Ann Liebert, Inc.
Description
Keywords
article, epidemic, gene sequence, heterosexuality, homosexuality, Human immunodeficiency virus 1, nonhuman, nucleotide sequence, phylogeny, polymerase chain reaction, priority journal, sexual transmission, South Africa, virus genome, virus strain, virus transmission, Base Sequence, Genome, Viral, HIV Infections, HIV-1, Humans, Male, Molecular Sequence Data, Phylogeny, Sequence Analysis, DNA, South Africa
Citation
AIDS Research and Human Retroviruses
23
12
23
12