Change in co-receptor usage of current South African HIV-1 subtype C primary isolates

Van Rensburg E.J. ; Smith T.-L. ; Zeier M. ; Robson B. ; Sampson C. ; Treurnicht F. ; Engelbrecht S. (2002)


Phenotypic analysis was performed on 13 HIV-1 strains isolated between 2000 and 2001. Syncytium-inducing and non-syncytium-inducing subtype C viruses were found, most of which used more than one co-receptor. For the first time subtype B viruses were isolated from South African heterosexual patients, a subtype previously associated only with homosexual spread in this geographical region.

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