Now showing items 1-3 of 3
Phenotypic analysis of peripheral B cell populations during mycobacterium tuberculosis infection and disease
(BioMed Central, 2016-07-29)
Background: Mycobacterium tuberculosis (Mtb) remains an unresolved threat resulting in great annual loss of life. The role of B cells during the protective immunity to Mtb is still unclear. B cells have been described as ...
Epigenetics and proteomics join transcriptomics in the quest for tuberculosis biomarkers
(American Society for Microbiology, 2015-09-15)
An estimated one-third of the world’s population is currently latently infected with Mycobacterium tuberculosis. Latent M. tuberculosis infection (LTBI) progresses into active tuberculosis (TB) disease in ~5 to 10% of ...
Detection of a combination of serum IgG and IgA antibodies against selected mycobacterial targets provides promising diagnostic signatures for active TB
(Impact Journals, 2017-03-24)
ENGLISH ABSTRACT: Immunoglobulin G (IgG) based tests for the diagnosis of active tuberculosis (TB) disease often show a lack of specificity in TB endemic regions, which is mainly due to a high background prevalence of ...