Now showing items 1-5 of 5
The functional response of B cells to antigenic stimulation : a preliminary report of latent tuberculosis
(Public Library of Science, 2016-04)
Mycobacterium tuberculosis (M.tb) remains a successful pathogen, causing tuberculosis disease numbers to constantly increase. Although great progress has been made in delineating the disease, the host-pathogen interaction ...
Phenotypic analysis of peripheral B cell populations during mycobacterium tuberculosis infection and disease
(BioMed Central, 2016-07-29)
Background: Mycobacterium tuberculosis (Mtb) remains an unresolved threat resulting in great annual loss of life. The role of B cells during the protective immunity to Mtb is still unclear. B cells have been described as ...
Diagnostic potential of novel salivary host biomarkers as candidates for the immunological diagnosis of tuberculosis disease and monitoring of tuberculosis treatment response
(Public Library of Science, 2016-08-03)
Background: There is an urgent need for new tools for the early diagnosis of TB disease and monitoring of the response to treatment, especially in resource-constrained settings. We investigated the usefulness of host ...
Identification of novel host biomarkers in plasma as candidates for the immunodiagnosis of tuberculosis disease and monitoring of tuberculosis treatment response
(Impact Journals, 2016-08-19)
ENGLISH ABSTRACT: There is an urgent need for new tools for the rapid diagnosis of tuberculosis disease. We evaluated the potentials of 74 host markers as biomarkers for the immunological diagnosis of tuberculosis and ...
Successful TB treatment induces B-cells expressing FASL and IL5RA mRNA
(Impact Journals, 2016-09)
ENGLISH ABSTRACT: Activated B-cells increase T-cell behaviour during autoimmune disease and other infections by means of cytokine production and antigen-presentation. Functional studies in experimental autoimmune ...