Now showing items 1-10 of 124
Redefining effusive-constrictive pericarditis with echocardiography
(Korean Society of Journal of Cardiovascular Ultrasound Office, 2016-12)
Background: Effusive-constrictive pericarditis (ECP) is traditionally diagnosed by using the expensive and invasive technique of direct pressure measurements in the pericardial space and the right atrium. The aim of this ...
A description of patients with recurrence of pulmonary tuberculosis in TB hospital, Ermelo
(Stellenbosch : University of Stellenbosch, 2015-07)
South Africa is one of the high burden countries for TB in Sub Sahara in Africa with Mpumalanga as one of the provinces with a high burden of disease. Data available on tuberculosis in Msukaligwa indicate the following: ...
The functional response of B cells to antigenic stimulation : a preliminary report of latent tuberculosis
(Public Library of Science, 2016-04)
Mycobacterium tuberculosis (M.tb) remains a successful pathogen, causing tuberculosis disease numbers to constantly increase. Although great progress has been made in delineating the disease, the host-pathogen interaction ...
Differential inhibition of adenylylated and deadenylylated forms of M. tuberculosis glutamine synthetase as a drug discovery platform
(Public Library of Science, 2017-03-29)
ENGLISH ABSTRACT: Glutamine synthetase is a ubiquitous central enzyme in nitrogen metabolism that is controlled by up to four regulatory mechanisms, including adenylylation of some or all of the twelve subunits by adenylyl ...
A phylogenomic investigation into the evolution and biological characteristics of the Beijing lineage family of principle genetic group 1 members of mycobacterium tuberculosis
(Stellenbosch : Stellenbosch University, 2016-12)
ENGLISH ABSTRACT : Tuberculosis has continued to be a global health concern and warrants an increased understanding of its causative agent Mycobacterium tuberculosis (M. tuberculosis) in terms of its evolution, virulence ...
The impact of mass media interventions on tuberculosis awareness, health-seeking behaviour and health service utilisation : a systematic review protocol
(BMJ Publishing Group, 2014-12)
Introduction: Tuberculosis (TB) is a serious public health problem in many parts of the world. Strategies to curb the spread of TB must match the multifaceted nature of the epidemic. The use of mass media is one of the ...
Susceptibility to tuberculosis is associated with PI3K-dependent increased mobilization of neutrophils
(Frontiers Media, 2018)
Neutrophilia is a condition commonly observed in patients with late-stage tuberculosis, but evidence suggests that increased neutrophil influx begins early after infection in susceptible hosts and functions to promote a ...
Elucidation of the substrates of mycosin 3, an essential protease of Mycobacterium tuberculosis
(Stellenbosch : University of Stellenbosch, 2011-03)
ENGLISH ABSTRACT: Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), infects one third of the world’s population and kills 1.7 million people per year. The increasing prevalence of multi- and extensively ...
An investigation into the role of collectins in tuberculosis infection
(Stellenbosch : Stellenbosch University, 2005-03)
ENGLISH ABSTRACT: Please see fulltext for abstract.
Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment
Anti-tuberculosis drug treatment is known to affect the number, phenotype, and effector functionality of antigen-specific T-cells. In order to objectively gauge Mycobacterium tuberculosis (MTB)-specific CD8+ T-cells at the ...