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The epidemiology and management of drug-resistant tuberculosis in childhood
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: Resistance to antituberculosis agents became evident soon after antituberculosis
treatment was introduced for the first time. Combined drug therapy seemed to resolve
this problem. Animal experimental ...
The interaction between human spermatozoa and its homologous zona pellucida : scientific advances and clinical significance
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: Infertility is a very common problem worldwide. Recent data have shown that disorders of the
male represent the most common single defined cause of infertility. This proposal examines
the clinical ...
The mycosins, a family of secreted subtilisin-like serine proteases associated with the immunologically-important ESAT-6 gene clusters of Mycobacterium tuberculosis
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: Pathogenic organisms frequently utilize proteases to perform specific functions related to
virulence. There is little information regarding the role of proteolysis in Mycobacterium tuberculosis
and no ...
Molecular identification and characterisation of rodent- and shrew-borne Hantaviruses
(Stellenbosch : University of Stellenbosch, 2010-12)
ENGLISH ABSTRACT: Throughout history disease entities have been described which match the
description of diseases now known to be caused by hantaviruses; however these
viruses were first identified as the aetiologic agent ...
Investigation of the relationship between genetic and environmental risk factors associated with obesity and insulin resistance in South African patients with non-alcoholic fatty liver disease(NAFLD)
(Stellenbosch : Stellenbosch University, 2012-12)
ENGLISH ABSTRACT: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease in the world. The disease spectrum of NAFLD extends from steatosis (types 1,2) to non-alcoholic steatohepatitis (NASH) ...
The occurance of genetic variations in the MYH9 gene and their association with CKD in a mixed South African population
(Stellenbosch : Stellenbosch University, 2012-12)
ENGLISH ABSTRACT: The purpose of this study was to investigate the association of the selected MYH9 single nucleotide polymorphisms (SNPs) with chronic kidney disease (CKD) and its related co-morbidities in the South African ...
Phenotypic factors influencing Mycobacterium tuberculosis phenotype
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT:
Please see fulltext for abstract.
Mycobacterium tuberculosis : genetic and phenotypic comparison
(Stellenbosch : Stellenbosch University, 2002-03)
ENGLISH ABSTRACT: This study exploits the Mycobacterium tuberculosis H37Rv genome sequence data in
the context of M. tuberculosis clinical isolates, to elucidate genetic variation, and examine the
phenotypic and molecular ...
Role of cyclic adenosine monophosphate (cAMP), cyclic guanosine monophosphate (cGMP) and p38 mitogen activated protein kinase (p38 MAPK) in preconditioning of the ischaemic myocardium
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: Ischaemic preconditioning (PC) is the phenomenon whereby a short episode of
coronary occlusion followed by reperfusion protects the myocardium against a
subsequent period of prolonged (also called index ...
The characterisation and expression of HIV-1 subtype C gag
(Stellenbosch : Stellenbosch University, 2002)
ENGLISH ABSTRACT: The gag gene of HIV-1 encodes for one of the major structural proteins, which
contains several conserved cytotoxic T cell (CTL) epitopes. Gag specific CTL
responses are important in controlling viral ...