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The mycosins, a family of secreted subtilisin-like serine proteases associated with the immunologically-important ESAT-6 gene clusters of Mycobacterium tuberculosis
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: Pathogenic organisms frequently utilize proteases to perform specific functions related to
virulence. There is little information regarding the role of proteolysis in Mycobacterium tuberculosis
and no ...
The role of corticotropin-releasing factor in anxiety disorders
(Stellenbosch : Stellenbosch University, 2001-12)
ENGLISH ABSTRACT: SEPARATION STUDY
Traumatic experiences during childhood can have a negative impact on behaviour
later in life. Kendier et al. (1992) found that the loss of a parent during childhood
increased the risk ...
The epidemiology and management of drug-resistant tuberculosis in childhood
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: Resistance to antituberculosis agents became evident soon after antituberculosis
treatment was introduced for the first time. Combined drug therapy seemed to resolve
this problem. Animal experimental ...
The interaction between human spermatozoa and its homologous zona pellucida : scientific advances and clinical significance
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: Infertility is a very common problem worldwide. Recent data have shown that disorders of the
male represent the most common single defined cause of infertility. This proposal examines
the clinical ...
The characterisation and expression of HIV-1 subtype C gag
(Stellenbosch : Stellenbosch University, 2002)
ENGLISH ABSTRACT: The gag gene of HIV-1 encodes for one of the major structural proteins, which
contains several conserved cytotoxic T cell (CTL) epitopes. Gag specific CTL
responses are important in controlling viral ...
Role of cyclic adenosine monophosphate (cAMP), cyclic guanosine monophosphate (cGMP) and p38 mitogen activated protein kinase (p38 MAPK) in preconditioning of the ischaemic myocardium
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: Ischaemic preconditioning (PC) is the phenomenon whereby a short episode of
coronary occlusion followed by reperfusion protects the myocardium against a
subsequent period of prolonged (also called index ...
Predictive value of normal sperm morphology in intrauterine insemination (IUI) : a structured literature review
(Stellenbosch : Stellenbosch University, 2001-12)
ENGLISH ABSTRACT: The aim of the study was to conduct a structured review of the literature published on the
use of normal sperm morphology, as an indicator of male fertility potential in intrauterine
insemination (M) ...
Alternative insulin mitogenic signaling pathways in immature osteoblast cell lines
(Stellenbosch : Stellenbosch University, 2002-03)
ENGLISH ABSTRACT: Insulin is a mitogen for many cells and commonly signals through the classical, mitogenic Raf-
MEK-ERK or metabolic PB-kinase pathways. Insulin deficiency or type I diabetes causes
severe osteopenia. ...
Community-based growth monitoring in a rural area lacking health facilities
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: A community-based growth monitoring (GM) project was established in a rural village in
KwaZulu-Natal. The project is an example of community-based activities that were based on a
participatory approach ...
Characterisation of the HIV-1 subtype C Env gene and the expression of the Env protein from selected isolates in mammalian cells
(Stellenbosch : Stellenbosch University, 2003-03)
ENGLISH ABSTRACT: At the end of 2002, human immunodeficiency virus (HIV) had infected 42 million people
worldwide. The morbidity and mortality rate, as well as the epidemic proportions of the
disease have led to ...