Now showing items 1-10 of 24
Beyond risk compensation : clusters of antiretroviral treatment (ART) users in sexual networks can modify the impact of ART on HIV incidence
(Public Library of Science, 2016)
Introduction: Concerns about risk compensation—increased risk behaviours in response to a perception of reduced HIV transmission risk—after the initiation of ART have largely been dispelled in empirical studies, but ...
HPTN 071 (PopART) : a cluster-randomized trial of the population impact of an HIV combination prevention intervention including universal testing and treatment : mathematical model
Background: The HPTN 052 trial confirmed that antiretroviral therapy (ART) can nearly eliminate HIV transmission from successfully treated HIV-infected individuals within couples. Here, we present the mathematical modeling ...
Missing HIV prevention opportunities in South African children – A 7-year review
(BioMed Central, 2014-12-13)
Background: The prevention of mother-to-child transmission (PMTCT) program in South Africa is now successful in ensuring HIV-free survival for most HIV-exposed children, but gaps in PMTCT coverage remain. The study ...
Shifting tasks from pharmacy to nonpharmacy personnel for providing antiretroviral therapy to people living with HIV : a systematic review and metaanalysis
(BMJ Publishing Group, 2017-8)
Objectives Lay people or non-pharmacy health workers with training could dispense antiretroviral therapy (ART) in resource-constrained countries, freeing up time for pharmacists to focus on more technical tasks. ...
The effect of sexually transmitted co-infections on HIV viral load amongst individuals on antiretroviral therapy : a systematic review and meta-analysis
(BioMed Central, 2015-06)
Background: Antiretroviral therapy (ART) markedly reduces HIV transmission, and testing and treatment programs have been advocated as a method for decreasing transmission at the population level. Little is known, ...
Inhibition of CYP2B6 by medicinal plant extracts : implication for use of efavirenz and nevirapine-based highly active anti-retroviral therapy (HAART) in resource-limited settings
Highly active antiretroviral therapy (HAART) has greatly improved health parameters of HIV infected individuals. However, there are several challenges associated with the chronic nature of HAART administration. For populations ...
Treatment of young children with HIV infection : using evidence to inform policymakers
(Public Library of Science, 2012-07-24)
No abstract available.
Antiviral efficacy and safety of abacavir-containing combination antiretroviral therapy as first-line treatment of HIV-infected children and adolescents : a systematic review protocol
(BioMed Central, 2014-08)
Abstract Background: Abacavir is one of the recommended nucleoside reverse transcriptase inhibitors (NRTIs) for the treatment of HIV infections among children and adolescents. However, there are concerns that the antiviral ...
Missed opportunities of inclusion in a cohort of HIV-infected children to initiate antiretroviral treatment before the age of two in West Africa, 2011 to 2013
(International AIDS Society, 2016-03-23)
Introduction: The World Health Organization (WHO) 2010 guidelines recommended to treat all HIV-infected children less than two years of age. We described the inclusion process and its correlates of HIV-infected children ...
Moderate to severe HIV-associated neurocognitive impairment : a randomized placebo-controlled trial of lithium
(Wolters Kluwer Health, 2016-11)
Background: HIV-associated neurocognitive disorder (HAND) remains highly prevalent despite effective anti-retroviral therapy (ART). A number of adjunctive pharmacotherapies for HAND have been studied with disappointing ...