Now showing items 1-10 of 15
Nevirapine plasma concentrations in premature infants exposed to single-dose nevirapine for prevention of mother-to-child transmission of HIV-1
(Health and Medical Publishing Group (HMPG), 2011-09)
Background. No pharmacokinetic data exist for premature infants receiving single-dose nevirapine (sd NVP) for prevention of mother-to-child transmission (MTCT) of HIV. Aim. To describe NVP decay pharmacokinetics in two ...
Monitoring the South African National Antiretroviral Treatment Programme, 2003-2007 : the IeDEA Southern Africa collaboration
(Health and Medical Publishing Group (HMPG), 2009-09)
Objectives. To introduce the combined South African cohorts of the International epidemiologic Databases to Evaluate AIDS Southern Africa (IeDEA-SA) collaboration as reflecting the South African national antiretroviral ...
Outcomes of the South African national antiretroviral treatment programme for children : the IeDEA southern Africa collaboration
(Health and Medical Publishing Group (HMPG), 2009-10)
Objectives. To assess paediatric antiretroviral treatment (ART) outcomes and their associations from a collaborative cohort representing 20% of the South African national treatment programme. Design and setting. Multi-cohort ...
When to start antiretroviral therapy in infants and children
(AOSIS OpenJournals, 2009-12)
This articles provides a background for antiretroviral therapy in infants and children, incorporating both old and new data. There is increasing data favouring early therapy for all age groups. Below a year of age, all ...
It is time to consider third-line options in antiretroviral-experienced paediatric patients?
(BioMed Central, 2011-11)
Abstract Background The historic use of full-dose ritonavir as part of an unboosted protease inhibitor (PI)-based antiretroviral therapy regimen in some South African children contributes to the frequent accumulation of ...
Early antiretroviral therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy : evidence from the Children with HIV Early antiretroviral therapy (CHER) Study.
Abstract Background Although otorrhea occurs commonly in HIV-infected infants, there are few data. We compared the incidence of otorrhea in infants receiving early vs deferred ART in the Children with HIV Early Antiretroviral ...
Trends in paediatric bloodstream infections at a South African referral hospital
(BioMed Central, 2015-04)
Background: The epidemiology of paediatric bloodstream infection (BSI) in Sub-Saharan Africa is poorly documented with limited data on hospital-acquired sepsis, impact of HIV infection, BSI trends and antimicrobial ...
High prevalence of lipoatrophy in pre-pubertal South African children on antiretroviral therapy : a cross-sectional study
(BioMed Central, 2012-11)
Background: Despite changes in WHO guidelines, stavudine is still used extensively for treatment of pediatric HIV in the developing world. Lipoatrophy in sub-Saharan African children can be stigmatizing and have far-reaching ...
HIV testing and antiretroviral therapy initiation at birth : views from a primary care setting in Khayelitsha
(AOSIS Publishing, 2015-04-28)
No abstract available.
Clinical presentation and outcome of tuberculosis in human immunodeficiency virus infected children on anti-retroviral therapy
(BioMed Central, 2008-01)
Background: The tuberculosis (TB) and human immunodeficiency virus (HIV) epidemics are poorly controlled in sub-Saharan Africa, where highly active antiretroviral treatment (HAART) has become more freely available. Little ...