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Maternal post-traumatic stress disorder, depression and alcohol dependence and child behaviour outcomes in mother–child dyads infected with HIV : a longitudinal study
(BMJ Publishing Group, 2013-12)
Objectives: HIV and psychiatric disorders are prevalent and often concurrent. Childbearing women are at an increased risk for both HIV and psychiatric disorders, specifically depression and post-traumatic stress disorder ...
Clinical presentation and outcome of tuberculosis in human immunodeficiency virus infected children on anti-retroviral therapy
(BioMed Central, 2008-01)
Background: The tuberculosis (TB) and human immunodeficiency virus (HIV) epidemics are poorly controlled in sub-Saharan Africa, where highly active antiretroviral treatment (HAART) has become more freely available. Little ...
High incidence of antimicrobial resistant organisms including extended spectrum beta-lactamase producing Enterobacteriaceae and methicillin-resistant Staphylococcus aureus in nasopharyngeal and blood isolates of HIV-infected children from Cape Town, South Africa
(BioMed Central, 2008-04)
Background: There is little information on nasopharyngeal (NP) flora or bacteremia in HIV-infected children. Our aim was to describe the organisms and antimicrobial resistance patterns in children enrolled in a prospective ...
Bacterial disease and antimicrobial susceptibility patterns in HIV-Infected, hospitalized children: A retrospective cohort study
(PLOS, 2008-09-24)
Background: Serious bacterial infections are a major source of morbidity and mortality in HIV-infected children. The
spectrum of disease is wide, and responsible organisms vary according to setting. The use of antibiotic ...
Nevirapine plasma concentrations in premature infants exposed to single-dose nevirapine for prevention of mother-to-child transmission of HIV-1
(Health and Medical Publishing Group (HMPG), 2011-09)
Background. No pharmacokinetic data exist for premature infants receiving single-dose nevirapine (sd NVP) for prevention of mother-to-child transmission (MTCT) of HIV. Aim. To describe NVP decay pharmacokinetics in two ...
Ensuring the involvement of children in the evaluation of new tuberculosis treatment regimens
(Public Library of Science (PLOS), 2008-08)
Global tuberculosis control is threatened by dramatic increases in HIV-related tuberculosis and by the emergence of multidrug-resistant strains. Highly lethal outbreaks of extensively drugresistant tuberculosis among ...
Mother-to-child transmission of hepatitis B virus in sub-Saharan Africa : time to act
(Elsevier, 2015-07)
What few people thought possible little more than a decade ago is now reality: scientific and operational advances are greatly reducing the number of deaths from HIV. The number of infant infections has decreased by 58% ...
Hepatitis B virus infection in HIV-exposed infants in the Western Cape, South Africa
(Elsevier, 2015-07)
Hepatitis B virus infection (HBV) is a significant public health problem in sub-Saharan Africa. Universal infant vaccination with the hepatitis B (HB) vaccine has been implemented within the South African Expanded Programme ...
It is time to consider third-line options in antiretroviral-experienced paediatric patients?
(BioMed Central, 2011-11)
Abstract Background The historic use of full-dose ritonavir as part of an unboosted protease inhibitor (PI)-based antiretroviral therapy regimen in some South African children contributes to the frequent accumulation of ...
Utility of clinical parameters to identify HIV infection in infants below ten weeks of age in South Africa : a prospective cohort study
(BioMed Central, 2011-11)
ABSTRACT: Background: As HIV-infected infants have high mortality, the World Health Organization now recommends initiating antiretroviral therapy as early as possible in the first year of life. However, in many settings, ...