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Evaluation of multiple cytokine levels to improve our understanding of protective immune responses against Tuberculosis and to develop novel diagnostic methods
(Stellenbosch : Stellenbosch University, 2013-03)
ENGLISH ABSTRACT: Important steps towards the global control of Tuberculosis include the improvement of diagnosis, the development of effective vaccines and the identification of correlates of protection/protective immunity ...
Utilization of antigen-specific host responses in the evaluation of Mycobacterium tuberculosis infection, development of disease and treatment effect
(Stellenbosch : Stellenbosch University, 2013-03)
ENGLISH ABSTRACT: Setting
This study was conducted in the Tygerberg district, Cape Town, in the Western Cape, South Africa
Background
The evaluation of early tuberculosis (TB) treatment response is based on month 2 ...
Refinements and innovations in biopsy and analysis techniques for pleural and lung disease
(Stellenbosch : University of Stellenbosch, 2007-12)
1.1. Background
Tumors arising from the lung, pleura, or chest wall are a frequent problem in clinical
pulmonary medicine. Most lesions are either infectious, neoplastic or granulomatous in
nature, but a variety of other ...
The investigation of peripheral blood cellular immune responses during infection with Mycobacterium Tuberculosis
(Stellenbosch : University of Stellenbosch, 2007-03)
Despite the ongoing global tuberculosis (TB) problem and extensive research into
protective immunity against this intracellular pathogen, mechanisms of protective
immunity against Mycobacterium tuberculosis (Mtb) in ...
Identification of immune correlates of natural protection against tuberculosis in a population with a high incidence of latent infection
(Stellenbosch : Stellenbosch University, 2008-03)
ENGLISH ABSTRACT: Setting
This study was conducted in the Tygerberg area of Cape Town in South Africa.
Background
A third of the world’s population is latently infected with Mycobacterium tuberculosis,
and correlates ...
Distinct immune profiles of recently exposed household contacts in a tuberculosis endemic setting in the Western Cape
(Stellenbosch : University of Stellenbosch, 2011-03)
Please refer to full text to view abstract.
Gene expression and cytokine pattern of pulmonary tuberculosis patients and their contacts in Ethiopia
(Stellenbosch : Stellenbosch University, 2013-03)
ENGLISH ABSTRACT: The immune response against M. tuberculosis is multifactorial, involving a network of innate
and adaptive immune responses. Characterization of the immune response, a clear
understanding of the dynamics ...
Immune parameters as biomarkers of Mycobacterium tuberculosis sterilization during anti-tuberculosis treatment
(Stellenbosch : Stellenbosch University, 2008-03)
ENGLISH ABSTRACT: Setting
Study conducted in Tygerberg, Cape Town in South Africa.
Hypothesis
Host biomarkers associated with the antimycobacterial immune response during active infection with M. tuberculosis and during ...
Clinical and laboratory investigation of latex allergy in healthcare workers
(Stellenbosch : Stellenbosch University, 2004-12)
ENGLISH ABSTRACT: Healthcare workers (HCWs) wear latex gloves to protect themselves and their patients against
the transmission of microbial, viral and bloodborne diseases. These individuals are primarily
exposed to ...
Evaluation of anti-tuberculosis responses in humans using different complementary immunological techniques
(Stellenbosch : Stellenbosch University, 2013-03)
ENGLISH ABSTRACT: Background
The QuantiFERON In-Tube (QFT IT) assay is an Interferon-gamma release assay
(IGRA) which is currently used to detect Mycobacterium tuberculosis (M. tb) infection. It
however cannot differentiate ...