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Now showing items 1-7 of 7
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The agreement between fasting glucose and markers of chronic glycaemic exposure in individuals with and without chronic kidney disease : a cross-sectional study
George, Cindy; Matsha, Tandi E.; Korf, Marizna; Zemlin, Annalise E.; Erasmus, Rajiv T.; Kengne, Andre P. (BMC (part of Springer Nature), 2020-01-30)Background: To assess whether the agreement between fasting glucose and glycated proteins is affected by chronic kidney disease (CKD) in a community-based sample of 1621 mixed-ancestry South Africans. Methods: CKD was ... -
An audit of 24-hour creatinine clearance measurements at Tygerberg Hospital and comparison with prediction equations
Le Riche, Mia; Zemlin, Annalise E.; Erasmus, Rajiv T.; Davids, MR (Health and Medical Publishing Group (HMPG), 2007-10)BACKGROUND: Internationally, clinical guidelines recommend the use of creatinine-based equations to estimate glomerular filtration rate (GFR) for assessment and follow-up of kidney disease. The routine use of 24-hour ... -
Coronavirus disease 2019 (COVID-19) and the reninangiotensin system : a closer look at angiotensin-converting enzyme 2 (ACE2)
Zemlin, Annalise E.; Wiese, Owen (Sage, 2020-05-01)ENGLISH ABSTRACT: Since the first cases of atypical pneumonia linked to the Huanan Seafood Wholesale Market in Wuhan, China were described in late December 2019, the global landscape has changed radically. In March 2020, ... -
HbA1c as a screening tool for diabetes mellitus and its use with traditional and novel biochemical parameters to predict cardiovascular risk in a local urban community
Zemlin, Annalise E. (Stellenbosch : Stellenbosh University, 2016-12)ENGLISH SUMMARY: Introduction The global obesity pandemic has reached Africa and the diabetes mellitus (DM) prevalence is increasing in parallel. A high prevalence of DM and risk for cardiovascular disease (CVD) has ... -
HbA1c of 6.5% to diagnose Diabetes Mellitus—Does it work for Us?—The Bellville South Africa study
Zemlin, Annalise E.; Matsha, Tandi E.; Hassan, Mogamat S.; Erasmus, Rajiv T. (Public Library of Science (PLOS), 2011-08)Background: HbA1c has been the gold standard for glycaemic control follow-up for decades. In 2009, a level of 6.5% (48 mmol/mol) was proposed as diagnostic for diabetes. We test this cut-off in our community. Methods: ... -
High molecular weight adiponectin levels are neither influenced by adiponectin polymorphisms nor associated with insulin resistance in mixed-ancestry hyperglycemic subjects from South Africa
Zemlin, Annalise E.; Matsha, Tandi E.; Kengne, Andre P.; Hon, Gloudina; Erasmus, Rajiv T. (De Gruyter Open, 2016)Background: High molecular weight (HMW) adiponectin has antiatherogenic, antiinflammatory and antidiabetic properties and these effects have been linked to its effect on high density lipoprotein cholesterol (HDL-c). Single ... -
Potential for medical error : incorrectly completed request forms for thyroid function tests limit pathologists' advice to clinicians
Zemlin, Annalise E.; Nutt, Louise; Burgess, Lesley J.; Eiman, Fredeline; Erasmus, Rajiv T. (Health and Medical Publishing Group (HMPG), 2009)Background. Various publications have highlighted the significance of laboratory errors in the pre- and post-analytical phases and their impact on results. Thyroid-stimulating hormone (TSH) is a first-line thyroid function ...