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Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics

Kriel, Jurgen; Muller-Nedebock, Kristian; Maarman, Gerald; Mbizana, Siyasanga; Ojuka, Edward; Klumperman, Bert; Loos, Ben (Nature Research, 2018-07-09)

Glioblastoma Multiforme (GBM) is known to be one of the most malignant and aggressive forms of brain cancer due to its resistance to chemotherapy. Recently, GBM was found to not only utilise both oxidative phosphorylation ...