Child with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosis
Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
BMJ Publishing Group
Abstract
We herein report a case of a child with tuberculous meningitis and COVID-19 coinfection complicated by hydrocephalus, arterial ischaemic stroke and extensive cerebral sinus venous thrombosis. Both conditions induce a proinflammatory cytokine drive resulting, among others, in a prothrombotic state. The disruption of the coagulation system in this case was supported by elevated D-dimers, fibrinogen and ferritin levels, consistent with thrombotic complications reported in some adult patients infected with COVID-19. The child also exhibited prolonged viral shedding that suggests severe disease.
Description
CITATION: Essajee Farida et al. 2020. Child with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosis. BMJ Case Reports, 2020:13, doi:10.1136/bcr-2020-238597.
The original publication is available at: https://casereports.bmj.com
The original publication is available at: https://casereports.bmj.com
Keywords
Meninges -- Tuberculosis, COVID-19 (Disease), Tuberculosis in children, Cerebral sinus venous thrombosis
Citation
Essajee Farida et al. 2020. Child with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosis. BMJ Case Reports, 2020:13, doi:10.1136/bcr-2020-238597