Rapid testing for respiratory syncytial virus in a resource-limited paediatric intensive care setting

Abstract
We analysed the performance characteristics of the respiratory syncytial virus lateral flow rapid antigen assay in use when compared to a multiplex polymerase chain reaction for detection of respiratory viruses. The study was conducted at a tertiary paediatric hospital in Port Elizabeth, South Africa, from 01 January 2017 to 31 December 2018. We found the clinical sensitivity (36.8%) of the rapid test to be too low for routine diagnostic use. Knowledge of assay performance characteristics of rapid tests are important for appropriate interpretation of rapid test results.
Description
Newman H, Tshabalala D, Mabunda S, et al. Rapid testing for respiratory syncytial virus in a resource-limited paediatric intensive care setting. Afr J Lab Med. 2020;9(1)
Keywords
respiratory syncytial virus, rapid antigen test, espiratory viruses, espiratory multiplex polymerase chain reaction
Citation
ewman H, Tshabalala D, Mabunda S, et al. Rapid testing for respiratory syncytial virus in a resource-limited paediatric intensive care setting. Afr J Lab Med. 2020;9(1),