Highly informative dinucleotide repeat polymorphism at the D11S29 locus on chromosome 11q23
Date
1992
Authors
Warnich L.
Groenewald I.
Theart L.
Retief A.E.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The informativeness of locus D11S29 as a genetic marker was improved by the identification of a highly polymorphic (GT)(n) repeat within the locus. Ten alleles were identified in parents of 40 Centre d'Etude du Polymorphisme Humain families and the polymorphism information content (PIC) was 0.77. The increased PIC value thus enables refinement of the linkage map of 11q23.
Description
Keywords
repetitive dna, article, chromosome 11q, dna polymorphism, gene locus, genetic linkage, human, priority journal, Alleles, Base Sequence, Chromosomes, Human, Pair 11, Female, Gene Frequency, Genetic Markers, Human, Linkage (Genetics), Male, Molecular Sequence Data, Pedigree, Polymerase Chain Reaction, Polymorphism (Genetics), Repetitive Sequences, Nucleic Acid, Support, Non-U.S. Gov't
Citation
Human Genetics
89
3
89
3