Tailoring hydrophilic N,N-dialkyl-N′-acylthioureas suitable for Pt(II), Pd(II) and Rh(III) chloride pre-concentration from acid aqueous solutions, and their complex separation by reversed-phase HPLC

Date
2003
Authors
Mautjana A.N.
Miller J.D.S.
Gie A.
Bourne S.A.
Koch K.R.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
A series of new, relatively hydrophilic, N,N-dialkyl-N′-(2,2- dimethylpropyl)thioureas (HLn) (n = 1, N,N-dimethyl-; n = 2, N-pyrrolidyl-; n = 3, N-piperidyl-) and their corresponding cis-[M(L n-S,O)2] [for M = Pt(II), Pd(II); n = 1-3] and fac-[Rh(Ln-S,O)3] (n = 2, 3) complexes have been prepared and characterised. The crystal and molecular structures of fac-tris(N- pyrrolidyl-N′-(2,2-dimethylpropyl)thioureato)rhodium(III) and cis-bis(N-piperidyl-N′-(2,2-dimethylpropyl)-thioureato)platinum(II) are reported, as representative examples. The favourable physiochemical properties and ready formation of stable mono-isomeric cis-[Pt(Ln-S,O) 2] and cis-[Pd(Ln-S,O)2] complexes with these ligands makes these compounds suitable for the reversed-phase high performance liquid chromatography (RP-HPLC) determination of traces of these metal ions in hydrochloric acid, following in situ complex formation in a homogeneous acetonitrile-hydrochloric acid phase and subsequent salt (NaCl) induced phase separation. A study of the effect of ligand structure on the separation behaviour of cis-[M(Ln-S,O)2] of Pd(n) and Pt(II) complexes has been undertaken, showing that the nature of the ligand has a significant influence on the separation characteristics of these complexes. © The Royal Society of Chemistry 2003.
Description
Keywords
Acetonitrile, Crystal structure, High performance liquid chromatography, Hydrophilicity, Isomers, Molecular structure, Phase separation, Ligand structure, Metal ions, Separation characteristics, Organometallics
Citation
Dalton Transactions
10