Characterization and cardiovascular effects of (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone, a diterpenoid isolated from Leonotis leonurus

Obikeze, Kene C. ; McKenzie, Jean M. ; Green, Ivan R. ; Mugaboa, Pierre (2008)

CITATION: Obikeze, K. C. et al. 2008. Characterization and cardiovascular effects of (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone, a diterpenoid isolated from Leonotis leonurus. South African Journal of Chemistry, 61:119-122.

The original publication is available at http://www.scielo.org.za

Article

A new diterpenoid, (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone (1), was isolated from Leonotis leonurus and the structure determined via NMR analysis. The compound causes significant changes in blood pressure of anaesthetized normotensive rats and exhibits a negative chronotropic effect.

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/108591
This item appears in the following collections: