Type

Now showing items 1-20 of 106

    • Adherence to isoniazid preventive chemotherapy: a prospective community based study 

      Marais, B. J.; Van Zyl, S.; Schaaf, H. S.; Van Aardt, M. C.; Gie, R. P.; Beyers, N. (BMJ Publishing Group, 2006-09)
      Background: Current international guidelines recommend 6–9 months of isoniazid (INH) preventive chemotherapy to prevent the development of active tuberculosis in children exposed to a susceptible strain of M tuberculosis. ...

    • Adrenal rest tumours in congenital adrenal hyperplasia 

      Zollner, Ekkehard W.; Pitcher, Richard (Journal of Endocrinology, Metabolism and Diabetes of South Africa (JEMDSA), 2008-07)
      Classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is rare, occurring approximately once in every 15 000 live births.1 At birth it is often suspected in girls because of ambiguous genitalia, ...

    • Age-disparity, sexual connectedness and HIV infection in disadvantaged communities around Cape Town, South Africa: A study protocol 

      Delva, Wim; Beauclair, Roxanne; Welte, Alex; Vansteelandt, Stijn; Hens, Niel; Aerts, Marc; Du Toit, Elizabeth; Beyers, Nulda; Temmerman, Marleen (BioMed Central Ltd, 2011)
      Abstract: Background Crucial connections between sexual network structure and the distribution of HIV remain inadequately understood, especially in regard to the role of concurrency and age disparity in relationships, and ...

    • Aggressive desmoid fibromatosis : first case in a Rwandan child 

      Kanyamuhunga, Aimable; McCall, Natalie; Tuyisenge, Lisine; Mumena, Crispus; Stefan, Daniela Cristina (Health & Medical Publishing Group, 2013-08-30)
      Desmoid tumours are a rare group of locally aggressive, non-malignant tumours of fibroblastic origin that can result in significant morbidity due to local invasion. Facial involvement in children with aggressive fibromatosis ...

    • Aminoglycoside-induced hearing loss in HIV-positive and HIV-negtive multidrug-resistant tuberculosis patients 

      Harris, Tashneem; Bardien, Soraya; Schaaf, H. Simon; Petersen, Lucretia; De Jong, Greetje; Fagan, Johannes J. (Health and Medical Publishing Group (HMPG), 2012-06)
      Background. Ototoxicity following aminoglycoside treatment for multidrug-resistant tuberculosis (MDR-TB), is a significant problem. This study documents the incidence of ototoxicity in HIVpositive and HIV-negative ...

    • Annual risk of tuberculous infection using different methods in communities with a high prevalence of TB and HIV in Zambia and South Africa 

      Shanaube, Kwame; Sisminidis, Charalambos; Ayles, Helen; Beyers, Nulda; Schaap, Ab; Lawrence, Katherine-Anne; Barker, Annie; Godfrey-Faussett, Peter (Public Library of Science (PLOS), 2009-11)
      Background: The annual risk of tuberculous infection (ARTI) is a key epidemiological indicator of the extent of transmission in a community. Several methods have been suggested to estimate the prevalence of tuberculous ...

    • Antiretroviral therapy for the management of HIV in children 

      Frigati, L.; Cotton, M.; Rabie, H. (Health & Medical Publishing Group, 2014-12)
      Since 2004, when antiretroviral therapy (ART) was first available to children through the National Department of Health, there has been significant progress in preventing and treating paediatric HIV. Large cohort studies ...

    • Assessing the impact of multidrug-resistant tuberculosis in children : an exploratory qualitative study 

      Franck, Caroline; Seddon, James A.; Hesseling, Anneke C.; Schaaf, H. S.; Skinner, Donald; Reynolds, Lucy (BioMed Central, 2014-08)
      Background: While the prevalence of multidrug-resistant (MDR) tuberculosis (TB) is high among children in the Western Cape of South Africa, the psychosocial implications of treatment for children with MDR-TB remain ...

    • The association between the ratio of monocytes : lymphocytes at age 3 months and risk of tuberculosis (TB) in the first two years of life 

      Naranbhai, Vivek; Kim, Soyeon; Fletcher, Helen; Cotton, Mark F.; Violari, Avy; Mitchell, Charles; Nachman, Sharon; McSherry, George; McShane, Helen; Hill, Adrian V. S.; Madhi, Shabir A. (BioMed Central, 2014-07-17)
      Background: Recent transcriptomic studies revived a hypothesis suggested by historical studies in rabbits that the ratio of peripheral blood monocytes to lymphocytes (ML) is associated with risk of tuberculosis (TB) ...

    • Bacterial disease and antimicrobial susceptibility patterns in HIV-Infected, hospitalized children: A retrospective cohort study 

      Jaspan, Heather B.; Huang, Lyen C.; Cotton, Mark F.; Whitelaw, Andrew; Myer, Landon (PLOS, 2008-09-24)
      Background: Serious bacterial infections are a major source of morbidity and mortality in HIV-infected children. The spectrum of disease is wide, and responsible organisms vary according to setting. The use of antibiotic ...

    • BCG vaccination in South African HIV-exposed infants : risks and benefits 

      Hesseling, A. C.; Caldwell, J.; Cotton, M. F.; Eley, B. S.; Jaspan, H. B.; Jennings, K.; Marais, B. J.; Nuttall, J.; Rabie, H.; Roux, P.; Schaaf, H. S. (Health and Medical Publishing Group (HMPG), 2009-02)

    • Bile peritonitis and miliary tuberculosis : A case report 

      Heydenrych J.J.; Du Toit D.F. (HMPG, 1977-09)
      ABSTRACT: We report an unusual case of bile peritonitis in a child. The literature on bile peritonitis is reviewed, and its treatment is discussed. According to the literature, bile peritonitis has a good prognosis ...

    • Binneaarse vogterapie in kinderchirurgie 

      Heydenrych, J. J. (Health and Medical Publishing Group (HMPG), 1975-03)
      From 1956 to 1969 we adopted a generous approach pertaining to the quantity of parenteral fluid required for paediatric surgery. Since 1970 we have changed our policy, and we now give smaller quantities during surgery ...

    • Bleeding in children with cancer 

      Dippenaar, Anel (Health and Medical Publishing Group (HMPG), 2010-07)
      Before the success story of leukaemia treatment started in the 1950s, many patients succumbed to the disease because of severe haemorrhage. A bleeding tendency is one of the hallmarks of haematological malignancies such ...

    • Burkitt lymphoma : epidemiological features and survival in a South African centre 

      Stefan, Daniela C.; Lutchman, Rabeen (BioMed Central, 2014-06)
      Background: The epidemiology of Burkitt Lymphoma (BL) shows that the endemic type is mainly confined to equatorial Africa and has a very close association with the Epstein-Barr virus (EBV), while the sporadic variant shows ...

    • Cancer in children -- Diagnosis -- South Africa 

      Kruger, Mariana (Health and Medical Publishing Group (HMPG), 2010-07)
      Childhood cancer is rare and comprises only 1% of all cancers. It usually develops from non-ectodermal embryonal tissue. Major improvement in cancer treatment and supportive care in the last 50 years has changed a fatal ...

    • Characteristics of clients who access mobile compared to clinic HIV counselling and testing services : a matched study from Cape Town, South Africa 

      Meehan, Sue-Ann; Naidoo, Pren; Claassens, Mareli M.; Lombard, Carl; Beyers, Nulda (BioMed Central, 2014-12)
      Background: Studies within sub-Saharan African countries have shown that mobile services increase uptake of HIV counselling and testing (HCT) services when compared to clinics and are able to access different ...

    • The characteristics of juvenile myasthenia gravis among South Africans 

      Heckmann, J. M.; Hansen, P.; Van Toorn, R.; Lubbe, E.; Janse Van Rensburg, E.; Wilmshurst, J. M. (Health and Medical Publishing Group (HMPG), 2012-06)
      Objectives. To report the characteristics of juvenile-onset (<20 years) myasthenia gravis (MG) in Africa. Subjects and methods. Six South African centres collected data which included acetylcholine receptor-antibody ...

    • A child with the nephrotic syndrome associated with endemic syphilis. : a case report 

      Le Roux, F. B.; Van Buuren, A. J. (Health and Medical Publishing Group (HMPG), 1978-07)
      A 21-month old infant with endemic syphilis who presented with nephrotic syndrome is described. Clinically, the features correlated well with those of renal disease associated with secondary syphilis. The onset of renal ...

    • Childhood cancer incidence in South Africa, 1987 - 2007 

      Stefan, D. C.; Stones, D. K.; Wainwright, D.; Kruger, M.; Davidson, A.; Poole, J.; Hadley, G. P.; Forman, D.; Colombet, M.; Steliarova-Foucher, E. (Health & Medical Publishing Group, 2015)
      Background. Childhood cancer is an emerging problem in Africa. Its extent is hazy because data are scarce, but it should be addressed. This is the first report from the South African Children’s Tumour Registry (SACTR), ...