Research Articles (Paediatrics and Child Health)

Paradoxical helminthiasis and giardiasis in Cape Town, South africa : epidemiology and control

Adams, Vera J. Markus, Miles B. Adams, Joanita F. A. Jordaan, Esme Curtis, Bronwyn Dhansay, Muhammad A. Obihara, Charlie C. Fincham, John E. (Makerere University Medical School, 2005-06)

Background. South Africa has endorsed a World Health Assembly (WHA) resolution calling for control of soil-transmitted helminths (STHs). In Cape Town, services and housing that exist in old-established suburbs should ...

The effect of a peptide-containing synthetic lung surfactant on gas exchange and lung mechanics in a rabbit model of surfactant depletion

Van Zyl, Johann M. Smith, Johan Hawtrey, Arthur (Dovepress, 2013-03)

Background: Currently, a new generation of synthetic pulmonary surfactants is being developed that may eventually replace animal-derived surfactants used in the treatment of respiratory distress syndrome. Enlightened by ...

Swallowing abnormalities in HIV infected children : an important cause of morbidity

Nel, Etienne D. Ellis, Alida (BioMed Central, 2012-06)

Background: Swallowing disorders, well recognised in adults, contribute to HIV-infection morbidity. Little data however is available for HIV-infected children. The purpose of this study is to describe swallowing disorders ...

High prevalence of lipoatrophy in pre-pubertal South African children on antiretroviral therapy : a cross-sectional study

Innes, Steve Cotton, Mark F. Haubrich, Richard Conradie, Maria M. Van Niekerk, Margaret Edson, Clair Rabie, Helena Jain, Sonia Sun, Xiaoying Zollner, Ekkehard W. Hough, Stephen Browne, Sara H. (BioMed Central, 2012-11)

Background: Despite changes in WHO guidelines, stavudine is still used extensively for treatment of pediatric HIV in the developing world. Lipoatrophy in sub-Saharan African children can be stigmatizing and have far-reaching ...

High prevalence of Tuberculosis and insufficient case detection in two communities in the Western Cape, South Africa

Claassens, Mareli Van Schalkwyk, Cari De Haan, Leonie Floyd, Sian Dunbar, Rory Van Helden, Paul Godfrey-Faussett, Peter Ayles, Helen Borgdorff, Martien Enarson, Donald Beyers, Nulda (PLoS ONE, 2013-04)

Background: In South Africa the estimated incidence of all forms of tuberculosis (TB) for 2008 was 960/100000. It was reported that all South Africans lived in districts with Directly Observed Therapy, Short-course. However, ...

Confidentiality in medicine

Kling, Sharon (Allergy Society of South Africa, 2010-11)

Confidentiality in medicine ensures respect for the patient's privacy and improves health care by enabling the patient to trust the health professional with very personal information. Confidentiality may be breached if ...

Ensuring the involvement of children in the evaluation of new tuberculosis treatment regimens

Burman, William J. Cotton, Mark F. Gibb, Diana M. Walker, A. Sarah Vernon, Andrew A. Donald, Peter R. (Public Library of Science (PLOS), 2008-08)

Global tuberculosis control is threatened by dramatic increases in HIV-related tuberculosis and by the emergence of multidrug-resistant strains. Highly lethal outbreaks of extensively drugresistant tuberculosis among ...

Changes in incidence and prognosis of malignancies in children with HIV

Stefan, Daniela C. Stones, David K. Newton, Rob (BioMed Central, 2012-04)

Aim: The aim of this study was to analyze the differences in patient demographics as well as in the relative incidence and outcome of childhood cancers, associated with the HIV infection.

Utility of clinical parameters to identify HIV infection in infants below ten weeks of age in South Africa : a prospective cohort study

Jaspan, Heather B. Myer, Landon Madhi, Shabir A. Violari, Avy Gibb, Diana M. Stevens, Wendy S. Dobbels, Els Cotton, Mark F. (BioMed Central, 2011-11)

ABSTRACT: Background: As HIV-infected infants have high mortality, the World Health Organization now recommends initiating antiretroviral therapy as early as possible in the first year of life. However, in many settings, ...

Supraventricular tachycardia in children

Van der Merwe, D. M. Van der Merwe, P. L. (Clinics Cardiv Publishing, 2004-04)

The mechanisms causing different supraventricular tachycardias can be identified with the aid of the 12-lead ECG using Tipple’s approach. The main aims of this retrospective study were to use the 12-lead ECG to determine ...

Mitral valve prolapse : a study of 45 children

Van der Ham, D. P. De Vries, J. K. Van der Merwe, P- L. (Clinics Cardiv Publishing, 2003-08)

The knowledge pertaining to mitral valve prolapse is mainly based on studies in adults. In this study, the clinical profile as described in adults was compared with that found in children up to the age of 13 years. Fortyfive ...

It is time to consider third-line options in antiretroviral-experienced paediatric patients?

Van Zyl, Gert U. Rabie, Helena Nuttall, James J. Cotton, Mark F. (BioMed Central, 2011-11)

Abstract Background The historic use of full-dose ritonavir as part of an unboosted protease inhibitor (PI)-based antiretroviral therapy regimen in some South African children contributes to the frequent accumulation of ...

Early antiretroviral therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy : evidence from the Children with HIV Early antiretroviral therapy (CHER) Study.

Hainline, Clotilde Taliep, Reghana Sorour, Gill Nachman, Sharon Rabie, Helena Dobbels, Els Janse van Rensburg, Anita Cornell, Morna Violari, Avy Madhi, Shabir A. Cotton, Mark F. (2011-10)

Abstract Background Although otorrhea occurs commonly in HIV-infected infants, there are few data. We compared the incidence of otorrhea in infants receiving early vs deferred ART in the Children with HIV Early Antiretroviral ...

Age-disparity, sexual connectedness and HIV infection in disadvantaged communities around Cape Town, South Africa: A study protocol

Delva, Wim Beauclair, Roxanne Welte, Alex Vansteelandt, Stijn Hens, Niel Aerts, Marc Du Toit, Elizabeth Beyers, Nulda Temmerman, Marleen (BioMed Central Ltd, 2011)

Abstract: Background Crucial connections between sexual network structure and the distribution of HIV remain inadequately understood, especially in regard to the role of concurrency and age disparity in relationships, and ...

Operational challenges in managing Isoniazid Preventive Therapy in child contacts : a high-burden setting perspective

Van Wyk, Susan S. Reid, Anthony J. Mandalakas, Anna M. Enarson, Donald A. Beyers, Nulda Morrison, Julie Hesseling, Anneke C. (2011-07-08)

Abstract Background The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five years of age in household contact with a ...

Research Articles (Paediatrics and Child Health)

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