SUNScholar
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Faculty of Medicine and Health Sciences
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Department of Surgical Sciences
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General Surgery
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Research Articles (General Surgery)
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Now showing items 1-3 of 3

Pharmacokinetics of recombinant activated factor VII in trauma patients with severe bleeding

Klitgaard, Thomas Tabanera y Palacios, Rene Boffard, Kenneth Lau, Philip T. C. Warren, Brian Rizoli, Sandro Rossaint, Rolf Kluger, Yoram Riou, Bruno (BioMed Central, 2006-07)

Introduction: Recombinant activated factor VII (rFVIIa) has been used as adjunctive therapy in trauma patients with severe bleeding. However, its pharmacokinetics profile remains unknown. Methods: In two placebo-controlled ...
Recombinant activated factor VII as an adjunctive therapy for bleeding control in severe trauma patients with coagulopathy : subgroup analysis from two randomized trials

Rizoli, Sandro B. Boffard, Kenneth D. Riou, Bruno Warren, Brian Iau, Philip Kluger, Yoram Rossaint, Rolf Tillinger, Michael NovoSeven Trauma Study Group (BioMed Central, 2006-12)

Introduction: We conducted a post-hoc analysis on the effect of recombinant factor VIIa (rFVIIa) on coagulopathic patients from two randomized, placebo-controlled, double-blind trials of rFVIIa as an adjunctive therapy for ...
Safety of rFVIIa in hemodynamically unstable polytrauma patients with traumatic brain injury : post hocanalysis of 30 patients from a prospective, randomized, placebo-controlled, double-blind clinical trial

Kluger, Yoram Riou, Bruno Rossaint, Rolf Rizoli, Sandro B. Boffard, Kenneth D. Choong, Philip Iau Tsau Warren, Brian Tillinger, Michael (BioMed Central, 2007-08)

Background: Trauma is a leading cause of mortality and morbidity, with traumatic brain injury (TBI) and uncontrolled hemorrhage responsible for the majority of these deaths. Recombinant activated factor VIIa (rFVIIa) is ...