Hypodipsic-hypernatremia syndrome in an adult with polycythemia : a case report

Chothia, Mogamat-Yazied ; George, Kiran ; Sheik, Muhammed ; Davids, Mogamat Razeen (2018-12-27)

CITATION: Chothia, M. Y., et al. 2019. Hypodipsic-hypernatremia syndrome in an adult with polycythemia : a case report. Journal of Medical Case Reports, 12:381, doi:10.1186/s13256-018-1938-y.

The original publication is available at https://jmedicalcasereports.biomedcentral.com

Article

Background: Hypernatremia is a very common electrolyte disorder and is frequently encountered in out-patient as well as in-hospital settings. We describe an adult who was found to have unexplained relative polycythemia and episodic hypernatremia. A diagnosis of idiopathic hypodipsic-hypernatremia syndrome was made and the patient was managed with a water-drinking schedule. Case presentation: A 24-year-old South African-Indian man was found to have polycythemia in association with episodes of hypernatremia. Investigations indicated that he had relative polycythemia. He experienced no thirst at a time when his serum sodium concentration was found to be 151 mmol/L. Further testing indicated that his renal response to arginine vasopressin was intact and magnetic resonance imaging of his brain revealed no hypothalamic lesions. A diagnosis of idiopathic hypodipsic-hypernatremia syndrome was made and he was managed with a water-drinking schedule that corrected his hypernatremia. Conclusion: Hypodipsia should always be considered when a patient without physical or cognitive disability presents with unexplained episodic hypernatremia or with relative polycythemia.

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/105328
This item appears in the following collections: