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Criteria for enhancing mucus transport : a systematic scoping review

dc.contributor.authorPieterse, Alisonen_ZA
dc.contributor.authorHanekom, Susan D.en_ZA
dc.date.accessioned2018-07-09T05:45:05Z
dc.date.available2018-07-09T05:45:05Z
dc.date.issued2018-07-06
dc.identifier.citationMultidisciplinary Respiratory Medicine. 2018 Jul 06;13(1):22
dc.identifier.citationPieterse, A. & Hanekom, S. D. 2018. Criteria for enhancing mucus transport : a systematic scoping review. Multidisciplinary Respiratory Medicine, 13:22, doi:10.1186/s40248-018-0127-6.
dc.identifier.issn2049-6958
dc.identifier.otherdoi:10.1186/s40248-018-0127-6
dc.identifier.urihttp://hdl.handle.net/10019.1/104126
dc.descriptionCITATION: Pieterse, A. & Hanekom, S. D. 2018. Criteria for enhancing mucus transport : a systematic scoping review. Multidisciplinary Respiratory Medicine, 13:22, doi:10.1186/s40248-018-0127-6.
dc.descriptionThe original publication is available at https://mrmjournal.biomedcentral.com
dc.description.abstractBackground: Uncertainty exists regarding the physiological basis of physiotherapy strategies to facilitate mucus clearance. The aim of this review was to describe the physiological factors and intrinsic conditions that facilitate airway mucus transport. Method: A scoping review was performed. A systematic literature search of six databases was executed. Eligibility criteria were applied by two researchers to reach the aim of the review. Papers were identified independently by two reviewers on title, abstract and full-text level. Any discrepancies were discussed with a third reviewer. Results: The search identified 35 papers published between 1975 and 2015. These differed significantly in terms of outcome measures, measurement techniques and methodologies and included animal studies, laboratory investigations, and the use of small human samples. Nine key factors influencing mucus transport were identified. These include: temperature and humidity, bronchial perfusion, ATP, forced expiratory technique and cough, generation of oscillation, ventilation patterns/airflow, epithelial differences, mucus properties and positioning. Conclusion: This review provides a framework for factors/conditions influencing mucus transport. Existing physiotherapy strategies for augmentation of airway mucus clearance can now be evaluated against the framework and new modalities informed.
dc.description.sponsorshipDivision of Physiotherapy, University of Stellenbosch
dc.description.urihttps://mrmjournal.biomedcentral.com/articles/10.1186/s40248-018-0127-6
dc.format.extent11 pages
dc.language.isoen
dc.publisherBioMed Central
dc.subjectAirway (Medicine)en_ZA
dc.titleCriteria for enhancing mucus transport : a systematic scoping reviewen_ZA
dc.typeArticle
dc.date.updated2018-07-08T03:46:25Z
dc.description.versionPublisher's version
dc.rights.holderAuthors retain copyright


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