CMC and phase separation studies of RAFT mediated amphiphilic diblock glycopolymers with methyl acrylate and styrene
Interesting new CMC and phase separation data of carbohydrate-based self-assembling core-shell nanoparticles which were synthesized via the Reversible Addition-Fragmentation Transfer (RAFT) process. The macro-RAFT agent, poly(3-O-Methacryloyl-1,2:5,6-di-O-isopropylidene-D-glucofuranose) (PMAlpGlc), was prepared by RAFT polymerization of the glycomonomer with cumyl phenyl dithioacetate as the chain transfer agent. Chain extension with styrene and methyl acrylate afforded the diblock copolymers (PMAlpGlc-b-styrene and PMAlpGlc-b-methyl acrylate) having predetermined molecular weight and narrow molecular weight distributions. Acidolysis of these diblock copolymers were undertaken and confirmed by NMR. Coreshell nanoparticles were observed by TEM. Copyright © 2007 WILEY-VCH Verlag GmbH & Co. KGaA.