Spoligotype signatures in the Mycobacterium tuberculosis complex

Streicher E.M. ; Victor T.C. ; Van Der Spuy G. ; Sola C. ; Rastogi N. ; Van Helden P.D. ; Warren R.M. (2007)


Evolution of the direct repeat region in Mycobacterium tuberculosis has created unique spoligotype signatures specifically associated with IS6110-defined strain families. Spoligotyping signatures may enable the analysis of the strain population structure in different settings and will enable the rapid identification of strain families that acquire drug resistance or escape protective immunity in drug and vaccine trials. Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/10114
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