Evaluation of the Capilia TB assay for culture confirmation of Mycobacterium tuberculosis infections in Zambia and South Africa

Muyoyeta M. ; De Haas P.E.W. ; Mueller D.H. ; Van Helden P.D. ; Mwenge L. ; Schaap A. ; Kruger C. ; Van Pittius N.C.G. ; Lawrence K. ; Beyers N. ; Godfrey-Faussett P. ; Ayles H. (2010)


The performance and cost of the Capilia TB assay were evaluated for use in a resource-limited setting. The sensitivity and specificity were 99.6% and 99.5%, respectively. The incremental costs of the Capilia test were estimated to be $1.46 and $1.84 when the test was added to liquid and solid culture processes, respectively. These findings suggest that the Capilia TB assay represents a rapid, simple, and inexpensive Mycobacterium tuberculosis identification test that can be used in resource-limited settings. Copyright © 2010, American Society for Microbiology. All Rights Reserved.

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