Centre for Evidence-Based Health Care
Recent Submissions
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Hepatitis B infection awareness, vaccine perceptions and uptake, and serological profile of a group of health care workers in Yaounde, Cameroon
(BioMed Central, 2016)ENGLISH SUMMARY : Background: Cameroon is one of the countries in Africa with the highest burden of Hepatitis B infection. Health care workers are known to be at risk of occupational exposure to blood and other infectious ...
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Assessing variability in results in systematic reviews of diagnostic studies
(BioMed Central, 2016)ENGLISH SUMMARY : Background: To describe approaches used in systematic reviews of diagnostic test accuracy studies for assessing variability in estimates of accuracy between studies and to provide guidance in this ...
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Interactive weekly mobile phone text messaging plus motivational interviewing in promotion of breastfeeding among women living with HIV in South Africa : study protocol for a randomized controlled trial
(BioMed Central, 2017-07-17)Background: South Africa recently phased out access to free formula milk in the public sector in support of breastfeeding for women living with HIV. Few women living with HIV in South Africa choose breastfeeding and among ...
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Changes in lipid profiles of HIV+ adults over nine months at a Harare HIV clinic : a longitudinal study
(Hindawi Publishing Corporation, 2016)ENGLISH SUMMARY : HIV infection, together with ART, is associated with changes in biochemical, metabolic parameters and lipid profiles. The aim of this study was to compare changes in lipid profiles among HIV positive ...
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Evaluating evidence-based health care teaching and learning in the undergraduate human nutrition; occupational therapy; physiotherapy; and speech, language and hearing therapy programs at a sub-Saharan African academic institution
(Public Library of Science, 2017-02-16)Background: It is important that all undergraduate healthcare students are equipped with evidence-based health care (EBHC) knowledge and skills to encourage evidence-informed decision-making after graduation. We assessed ...
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Building capacity in clinical epidemiology in Africa : experiences from Masters programmes
(BioMed Central, 2017-02-27)ENGLISH SUMMARY : Background: To describe and contrast programmatic offering of Clinical Epidemiology Masters programmes in Africa, to evaluate experiences of graduates and faculty, and assess if graduates are playing ...
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Correlation of rpoB mutations with minimal inhibitory concentration of rifampin and rifabutin in Mycobacterium tuberculosis in an HIV/AIDS endemic setting, South Africa
(Frontiers, 2016-12-05)ENGLISH SUMMARY : Treatment of tuberculosis (TB) and HIV co-infections is often complicated by drug-to-drug interactions between anti-mycobacterial and anti-retroviral agents. Rifabutin (RFB) is an alternative to rifampin ...
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The epidemiology of tuberculosis in health care workers in South Africa : a systematic review
(BioMed Central, 2016-08-20)ENGLISH SUMMARY : Background: In South Africa, workplace acquired tuberculosis (TB) is a significant occupational problem among health care workers. In order to manage the problem effectively it is important to know the ...
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South African clinical practice guidelines quality measured with complex and rapid appraisal instruments
(BioMed Central, 2016-04-27)ENGLISH SUMMARY : Background: Critically appraising the quality of clinical practice guidelines (CPGs) is an essential element of evidence implementation. Critical appraisal considers the quality of CPG construction and ...
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To adopt, to adapt, or to contextualise? The big question in clinical practice guideline development
(BioMed Central, 2016-09-13)ENGLISH SUMMARY : Aim: Developing new clinical practice guidelines (CPGs) can be time-consuming and expensive. A more efficient approach could be to adopt, adapt or contextualise recommendations from existing good quality ...
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Research evidence and policy : qualitative study in selected provinces in South Africa and Cameroon
(BioMed Central, 2015-09-03)ENGLISH SUMMARY : Background: The translation of research into policy and practice is enhanced by policymakers who can recognise and articulate their information needs and researchers that understand the policymakers’ ...
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Mapping South African allied health primary care clinical guideline activity : establishing a stakeholder reference sample
(BioMed Central, 2016-10-10)ENGLISH SUMMARY : Background: Little is known about allied health (AH) clinical practice guideline (CPG) activity in South Africa, and particularly in relation to primary health care (PHC). This paper reports on a scoping ...
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Developing the African national health research systems barometer
(BioMed Central, 2016-07-22)ENGLISH SUMMARY : Background: A functional national health research system (NHRS) is crucial in strengthening a country’s health system to promote, restore and maintain the health status of its population. Progress towards ...
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Enhancing evidence informed policymaking in complex health systems : lessons from multi-site collaborative approaches
(BioMed Central, 2016-03-17)ENGLISH SUMMARY : Background: There is an increasing interest worldwide to ensure evidence-informed health policymaking as a means to improve health systems performance. There is a need to engage policymakers in collaborative ...
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The prevalence of type 2 diabetes mellitus among older people in Africa : a systematic review study protocol
(BMJ Publishing Group, 2014-05)Introduction: The number of people with diabetes in Africa is projected to increase substantially in the next two decades, due to factors including rapid urbanisation, adoption of unhealthy diets and exercise patterns and ...
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Systematic review of the effects of iodised salt and iodine supplements on prenatal and postnatal growth : study protocol
(BMJ Publishing Group, 2015-11)Introduction: Iodine is an essential micronutrient and component of the thyroid hormones. Sufficient ingestion of iodine is necessary for normal growth and development. If iodine requirements are not met, growth can be ...
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High risk of malnutrition associated with depressive symptoms in older South Africans living in KwaZulu-Natal, South Africa : a cross-sectional survey
(BioMed Central, 2015-10)Background: Malnutrition contributes to functional and cognitive decline in older adults, which results in decreased quality of life and loss of independence. This study aimed to identify determinants of nutritional risk ...
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Iodised salt and iodine supplements for prenatal and postnatal growth : a rapid scoping of existing systematic reviews
(BioMed Central, 2015-09)Background: Iodine deficiency can adversely affect child development including stunted growth. However, the effect of iodine supplementation or fortification on prenatal and postnatal growth in children (<18 years) is ...
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Prevalence of arthritis in Africa : a systematic review and meta-analysis
(Public Library of Science, 2015-08)Objective: In this systematic review, we estimate the prevalence of six types of arthritis in Africa; namely rheumatoid arthritis, osteoarthritis, juvenile arthritis, psoriatic arthritis, gout, and ankylosing ...
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Patience, persistence and pragmatism : experiences and lessons learnt from the implementation of clinically integrated teaching and learning of evidence-based health care – a qualitative study
(Public Library of Science, 2015-06)Background: Clinically integrated teaching and learning are regarded as the best options for improving evidence-based healthcare (EBHC) knowledge, skills and attitudes. To inform implementation of such strategies, we ...
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Pre-hospital antibiotics for open fractures : is there time?
(Champagne Media, 2014)Early administration of intravenous (IV) antibiotics providing cover against Gram positive and negative organisms can be argued to be the single most important factor in reducing infection rate in patients with open ...
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Incorporating quality assessments of primary studies in the conclusions of diagnostic accuracy reviews : a cross-sectional study
(BioMed Central, 2014-03-03)Background: Drawing conclusions from systematic reviews of test accuracy studies without considering the methodological quality (risk of bias) of included studies may lead to unwarranted optimism about the value of ...
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Exploration of supervisor and student experiences during master’s studies in a health science faculty
(HESA, 2016)Significant growth in postgraduate student numbers with seemingly little change in staff composition and supervision capacity have prompted the need for research into the experiences of supervisors in a diverse interdisciplinary ...
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Efficacy and safety of abacavir-containing combination antiretroviral therapy as first-line treatment of HIV infected children and adolescents : a systematic review and meta-analysis
(BioMed Central, 2015-10)Background: Abacavir is one of the recommended nucleoside reverse transcriptase inhibitors (NRTIs) for the treatment of HIV infections among children and adolescents. However, there are concerns that the antiviral ...
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High prevalence of cardiovascular risk factors in Durban South African Indians : the Phoenix Lifestyle Project
(Health & Medical Publishing Group, 2016-02)Background. Previous studies show a high prevalence of cardiovascular (CV) risk factors in South African (SA) Asian Indians, with the emergence of premature coronary artery disease in young Indian subjects. Objective. To ...
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What are the effects of teaching evidence-based health care (EBHC)? : overview of systematic reviews
(PLoS, 2014-01)Background: An evidence-based approach to health care is recognized internationally as a key competency for healthcare practitioners. This overview systematically evaluated and organized evidence from systematic reviews ...
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Differences in functional outcomes for adult patients with prosthodontically-treated and -untreated shortened dental arches : a systematic review
(PLoS, 2014-07)This review examined differences in functional outcomes and patient satisfaction when shortened dental arches are left untreated compared to their restoration to complete arch lengths with different prosthodontic ...
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Methods used and lessons learnt in conducting document reviews of medical and allied health curricula : a key step in curriculum evaluation
(BioMed Central, 2014-11)Background: This paper describes the process, our experience and the lessons learnt in doing document reviews of health science curricula. Since we could not find relevant literature to guide us on how to ...
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Understanding interventions for improving routine immunization coverage in children in low- and middle-income countries : a systematic review protocol
(BioMed Central, 2013-11)Background: Virtually all low- and middle-income countries are dependent on the World Health Organization’s Expanded Program on Immunization for delivery of vaccines to children. The Expanded Program on Immunization ...
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Low hepatitis B vaccine uptake among surgical residents in Cameroon
(BioMed Central, 2014-03)Background: Hepatitis B virus (HBV) infection is one of the most serious occupational hazards faced by healthcare workers. Surgical personnel are particularly at risk. HBV infection is preventable by vaccination, but no ...
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