Centre for Evidence-Based Health Care

 

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Recent Submissions

  • Calcium channel blockers for people with chronic kidney disease requiring dialysis 

    Esterhuizen, T. M.; Mugendi, G. A.; Strippoli, G. F. M.; Mutua, F. M. (Cochrane, 2014)
    This is the protocol for a review and there is no abstract. The objectives are as follows: This review aims to look at the benefits and harms of CCB for people with CKD requiring dialysis.

  • Task shifting from doctors to non-doctors for initiation and maintenance of antiretroviral therapy 

    Adeniyi, F. B.; Kredo, T.; Bateganya, M.; Pienaar, E. D. (Cochrane, 2014)
    Background: The high levels of healthcare worker shortage is recognised as a severe impediment to increasing patients’ access to antiretroviral therapy. This is particularly of concern where the burden of disease is ...

  • Transcutaneous screening for hyperbilirubinemia in neonates 

    Smith, J.; Uthman, O. A.; Okwundu, C. I. (Cochrane, 2014)
    This is the protocol for a review and there is no abstract. The objectives are as follows: To evaluate to the effects of transcutaneous screening for hyperbilirubinemia to prevent the readmission of neonates for phototherapy.

  • Nutritional supplements for people being treated for active tuberculosis 

    Grobler, Liesl; Nagpal, Sukrti; Sudarsanam, Thambu D.; Sinclair, David (Cochrane, 2016-06-29)
    Background: Tuberculosis and malnutrition are linked in a complex relationship. Tuberculosis may cause undernutrition through increasedmetabolic demands and decreased intake, and nutritional deficiencies may worsen the ...

  • Public stewardship of private for-profit healthcare providers in low- and middle-income countries 

    Wiysonge, Charles S.; Abdullahi, Leila H.; Ndze, Valantine N.; Hussey, Gregory D. (Cochrane, 2016-08-11)
    Background: Governments use different approaches to ensure that private for-profit healthcare services meet certain quality standards. Such government guidance, referred to as public stewardship, encompasses government ...

  • Brief school-based interventions and behavioural outcomes for substance-using adolescents 

    Okwundu, Charles I.; Louw, Johann; Myers, Bronwyn J.; Carney, Tara (Cochrane, 2016-01-20)
    Background: Adolescent substance use is a major problem in and of itself, and because it acts as a risk factor for other problem behaviours. As substance use during adolescence can lead to adverse and often long-term ...

  • Interventions for improving coverage of childhood immunisation in low- and middle-income countries 

    Wiysonge, Charles S.; Oyo-Ita, Angela; Oringanje, Chioma; Nwachukwu, Chukwuemeka E.; Oduwole, Olabisi; Meremikwu, Martin M. (Cochrane, 2016-07-10)
    Background: Immunisation is a powerful public health strategy for improving child survival, not only by directly combating key diseases that kill children but also by providing a platform for other health services. However, ...

  • Barriers and enablers for the development and implementation of allied health clinical practice guidelines in South African primary healthcare settings : a qualitative study 

    Dizon, J. M.; Grimmer, K.; Louw, Q.; Machingaidze, S.; Parker, H.; Pillen, H. (BioMed Central, 2017)
    Background: The South African allied health (AH) primary healthcare (PHC) workforce is challenged with the complex rehabilitation needs of escalating patient numbers. The application of evidence-based care using clinical ...

  • Vector and reservoir control for preventing leishmaniasis 

    Esterhuizen, Tonya; Gonzalez, Urba; Pinart, Mariona; Sinclair, David; Firooz, Alireza; Enk, Claes; Velez, Ivan D.; Tristan, Mario; Alvar, Jorge (Cochrane, 2015-08-05)
    Background: Leishmaniasis is caused by the Leishmania parasite, and transmitted by infected phlebotomine sandflies. Of the two distinct clinical syndromes, cutaneous leishmaniasis (CL) affects the skin and mucous membranes, ...

  • Treatments for breast abscesses in breastfeeding women 

    Irusen, Priyadarshani Hayley; Rohwer, Anke Cornelia; Steyn, D. Wilhelm; Young, Taryn (Cochrane, 2015-08-17)
    Background: The benefits of breastfeeding are well known, and the World Health Organization recommends exclusive breastfeeding for the first six months of life and continuing breastfeeding to age two. However, many women ...

  • Interventions for preventing postpartum constipation 

    Turawa, Eunice Bolanle; Musekiwa, Alfred; Rohwer, Anke Cornelia (Cochrane, 2015-09-18)
    Background: Postpartum constipation, with symptoms such as pain or discomfort, straining, and hard stool, is a common condition affecting mothers. Haemorrhoids, pain at the episiotomy site, effects of pregnancy hormones ...

  • Intermittent preventive antimalarial treatment for children with anaemia 

    Rohwer, Anke Cornelia; Athuman, Mwaka; Kabanywanyi, Abdunoor M. (Cochrane, 2015-01-03)
    Background: Anaemia is a global public health problem. Children under five years of age living in developing countries (mostly Africa and South- East Asia) are highly affected. Although the causes for anaemia are ...

  • Incentives and enablers to improve adherence in tuberculosis 

    Wiysonge, Charles Shey Umaru; Lutge, Elizabeth E.; Knight, Stephen E.; Sinclair, David; Volmink, Jimmy (Cochrane, 2015-09-03)
    Background: Patient adherence to medications, particularly for conditions requiring prolonged treatment such as tuberculosis (TB), is frequently less than ideal and can result in poor treatment outcomes. Material incentives ...

  • Improving vaccination uptake among adolescents 

    Wiysonge, Charles Shey Umaru; Abdullahi, Leila H.; Kagina, Benjamin M. N.; Hussey, Gregory D. (Cochrane, 2015-09-29)
    This is the protocol for a review and there is no abstract. The objectives are as follows: To evaluate the effects of interventions to improve vaccine uptake among adolescents in low, middle and high-income countries.

  • Government regulation of private health insurance 

    Wiysonge, Charles Shey Umaru; Motaze, Nkengafac V.; Chi, Che P.; Ongolo-Zogo, Pierre; Ndongo, Jean Serge (Cochrane, 2015-04-17)
    This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The objective of this review is to assess the effects of policies that regulate private health insurance.

  • Fetal movement counting for assessment of fetal wellbeing 

    Hofmeyr, George Justus; Mangesi, Lindeka; Smith, Valerie; Smyth, Rebecca M. D. (Cochrane, 2015-10-15)
    Background : Fetal movement counting is a method by which a woman quantifies the movements she feels to assess the condition of her baby. The purpose is to try to reduce perinatal mortality by alerting caregivers when ...

  • Community-level interventions for improving access to food in low- and middle-income countries 

    Schoonees, Anel; Durao, Solange; Ramokolo, Vundli; Oliveira, Julicristie Machado De; Kristjansson, Elizabeth (Cochrane, 2015-02-02)
    This is the protocol for a review and there is no abstract. The objectives are as follows: Primary objective : To determine the effects of community-level interventions that aim to improve access to nutritious food in ...

  • Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas 

    Ochodo, Eleanor Atieno; Gopalakrishna, Gowri; Spek, Bea; Reitsma, Johannes B.; Van Lieshout, Lisette; Polman, Katja; Lamberton, Poppy; Bossuyt, Patrick M. M.; Leeflang, Mariska M. G. (Cochrane, 2015-03-11)
    Background : Point-of-care (POC) tests for diagnosing schistosomiasis include tests based on circulating antigen detection and urine reagent strip tests. If they had sufficient diagnostic accuracy they could replace ...

  • Vitamin A supplements for reducing mother-to-child HIV transmission 

    Wiysonge, Charles S.; Ndze, Valantine N.; Kongnyuy, Eugene J.; Shey, Muki S. (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)
    Background: Strategies to reduce the risk of mother‐to‐child transmission of the human immunodeficiency virus (HIV) include lifelong antiretroviral therapy (ART) for HIV‐positive women, exclusive breastfeeding from birth ...

  • Authorship, plagiarism and conflict of interest : views and practices from low/ middle-income country health researchers 

    Rohwer, Anke; Young, Taryn; Wager, Elizabeth; Garner, Paul (BMJ Publishing Group, 2017-11)
    Objectives To document low/middle-income country (LMIC) health researchers’ views about authorship, redundant publication, plagiarism and conflicts of interest and how common poor practice was in their institutions. Design ...

  • Protocol for a qualitative synthesis of barriers and facilitators in implementing guidelines for diagnosis of tuberculosis 

    Ochodo, Eleanor; Kredo, Tamara; Young, Taryn; Wiysonge, Charles Shey (BMJ Publishing Group, 2017-6)
    Introduction Despite the introduction of new tests and guidelines for diagnosis of tuberculosis (TB), worldwide case detection rate of TB is still suboptimal. This could be in part explained by the poor implementation ...

  • Epidemiology of rubella infection in Cameroon : a 7-year experience of measles and rubella case-based surveillance, 2008–2014 

    Nimpa Mengouo, Marcellin; Ndze, Valantine Ngum; Baonga, Frangy; Kobela, Marie; Wiysonge, Charles Shey (BMJ Publishing Group, 2017-4)
    Objective The aim of this study was to estimate the proportion of rubella disease in a measles case-based surveillance in Cameroon prior to rubella vaccine introduction into the national immunisation programme. Design ...

  • Procalcitonin, C-reactive protein, and presepsin for the diagnosis of sepsis in adults and children 

    Onyenekwu, Chinelo P.; Okwundu, Charles I.; Ochodo, Eleanor A. (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)
    This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows: The objectives of this review are: - To assess the diagnostic accuracy of PCT, CRP and presepsin for sepsis in adults ...

  • Isoniazid for preventing tuberculosis in HIV-infected children 

    Zunza, Moleen; Gray, Diane M.; Young, Taryn; Cotton, Mark; Zar, Heather J. (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)
    Background: Tuberculosis (TB) is an important cause of illness and death in HIV‐positive children living in areas of high TB prevalence. We know that isoniazid prophylaxis prevents TB in HIV‐negative children following TB ...

  • Interventions for treating tuberculous pericarditis 

    Wiysonge, Charles S.; Ntsekhe, Mpiko; Thabane, Lehana; Volmink, Jimmy; Majombozi, Dumisani; Gumedze, Freedom; Pandie, Shaheen; Mayosi, Bongani M. (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)
    Background: Tuberculous pericarditis – tuberculosis infection of the pericardial membrane (pericardium) covering the heart – is becoming more common. The infection can result in fluid around the heart or fibrosis of the ...

  • Transcutaneous bilirubinometry versus total serum bilirubin measurement for newborns 

    Okwundu, C. I.; Uthman, O. A.; Suresh, G.; Smith, J.; Wiysonge, C. S.; Bhutani, V. K. (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)
    This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows: - To determine the diagnostic accuracy of TcB as: i) a diagnostic test for hyperbilirubinaemia in newborns suspected to ...

  • Interventions for improving adults’ use of primary oral health care services 

    Harris, Rebecca; Raison, Heather; Christian, Bradley; Bakare, Lawal; Okwundu, Charles I.; Burnside, Girvan (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)
    This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effectiveness of interventions aimed at improving adults’ use of primary dental care services in order to improve their ...

  • Implementation strategies for health systems in low-income countries : an overview of systematic reviews 

    Pantoja, Tomas; Opiyo, Newton; Lewin, Simon; Paulsen, Elizabeth; Ciapponi, Agustin; Wiysonge, Charles S.; Herrera, Cristian A.; Rada, Gabriel; Penaloza, Blanca; Dudley, Lilian; Gagnon, Marie-Pierre; Marti, Sebastian Garcia; Oxman, Andrew D. (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)
    Background: A key function of health systems is implementing interventions to improve health, but coverage of essential health interventions remains low in low‐income countries. Implementing interventions can be challenging, ...

  • Governance arrangements for health systems in low-income countries : an overview of systematic reviews 

    Herrera, Cristian A.; Lewin, Simon; Paulsen, Elizabeth; Ciapponi, Agustin; Opiyo, Newton; Pantoja, Tomas; Rada, Gabriel; Wiysonge, Charles S.; Bastias, Gabriel; Marti, Sebastian Garcia; Okwundu, Charles I.; Penaloza, Blanca; Oxman, Andrew D. (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)
    Background: Governance arrangements include changes in rules or processes that determine authority and accountability for health policies, organisations, commercial products and health professionals, as well as the involvement ...

  • Interleukin-2 as an adjunct to antiretroviral therapy for HIV-positive adults 

    Onwumeh, Jennifer; Okwundu, Charles I.; Kredo, Tamara (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)
    Background: Human immunodeficiency virus (HIV) continues to be a leading cause of morbidity and mortality, particularly in sub‐Saharan Africa. Although antiretroviral drugs have helped to improve the quality of life and ...

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