Search

Now showing items 1-2 of 2

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response

Matsumiya, Magali; Harris, Stephanie A.; Satti, Iman; Stockdale, Lisa; Tanner, Rachel; O’Shea, Matthew K.; Tameris, Michelle; Mahomed, Hassan; Hatherill, Mark; Scriba, Thomas J.; Hanekom, Willem A.; McShane, Helen; Fletcher, Helen A. (BioMed Central, 2014-06)

Background: Tuberculosis (TB) remains a global health problem, with vaccination likely to be a necessary part of a successful control strategy. Results of the first Phase 2b efficacy trial of a candidate vaccine, MVA85A, ...

The candidate TB vaccine, MVA85A, induces highly durable Th1 responses

Tameris, Michele; Geldenhuys, Hennie; Luabeya, Angelique KanyKany; Smit, Erica; Hughes, Jane E.; Vermaak, Samantha; Hanekom, Willem A.; Hatherill, Mark; Mahomed, Hassan; McShane, Helen; Scriba, Thomas J. (PLoS, 2014-02)

Background: Vaccination against tuberculosis (TB) should provide long-term protective immunity against Mycobacterium tuberculosis (M.tb). The current TB vaccine, Bacille Calmette-Guerin (BCG), protects against disseminated ...