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Trends in mortality and factors associated with mortality and morbidity amongst hospitalized low birth weigth infants at a tertiary level hospital in Cameroon, 2001-2005

dc.contributor.advisorEsterhuizen, Tonyaen_ZA
dc.contributor.advisorKoum, Danielle Christiane Kedyen_ZA
dc.contributor.authorWiyeh, Alison Beriliyen_ZA
dc.contributor.otherStellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Interdisciplinary Health Sciences. Community Health.en_ZA
dc.date.accessioned2016-12-22T13:07:18Z
dc.date.available2016-12-22T13:07:18Z
dc.date.issued2016-12
dc.identifier.urihttp://hdl.handle.net/10019.1/100030
dc.descriptionThesis (MSc)--Stellenbosch University, 2016.
dc.description.abstractENGLISH SUMMARY : Background: Babies born with a birth weight of less than 2500grams have a low birth weight (LBW) and death amongst them accounts for 80% of all neonatal deaths. At the endpoint of the Millennium Development Goals (MDGs), we evaluate the progress made by Laquintinie hospital, Cameroon in reducing mortality amongst low birth weight babies, and identify factors associated with their morbidity and mortality. Methods: We estimated the mortality rates amongst LBW infants from 2001 to 2015, using a retrospective cohort study. Hospital records from 2001 to 2014, and the medical files for 2015 of LBW infants hospitalized in this hospital were used to evaluate their outcomes and factors associated with their morbidity and mortality. Findings: The overall mortality rate progressively increased from 19·9% in 2001 to 50·7% in 2015, with the greatest increase observed amongst extremely low birth weight infants (ELBW). In time series analysis, ELBW infants Beta 0·49 (95% CI 0.12 - 0.87) and incremental year of birth Beta 1·4 (95% CI 1.04 - 1.81) accounted for the increase in mortality rate. ELBW (OR: 4·3, 95% CI ), VLBW (OR: 2·7, 95% CI ) and apgar <7 at 5 minutes (OR: 25, P=0·022) were risk factors for respiratory morbidity. Apgar <7 at 5 minutes (OR: 5·5, P<0·001) was a risk factor for neurological morbidity. Factors associated with mortality were VLBW (OR: 4·7 P<0·001), respiratory distress (OR: 9·2, P<0·001), apnoea (OR: 4·2, P0·004) and gastrointestinal haemorrhage (OR: 5·839, P<0·001). Interpretation: The mortality rates amongst low birth weight infants hospitalized at Laquintinie Hospital, increased in the period 2001-2015, and negatively impacted its achievement of MDG 4.en_ZA
dc.description.abstractAFRIKAANSE OPSOMMING : Geen opsomming beskikbaar.af_ZA
dc.format.extent54 pages ; illustrations
dc.language.isoen_ZAen_ZA
dc.publisherStellenbosch : Stellenbosch University
dc.subjectInfants -- Mortalityen_ZA
dc.subjectBirth weight, Lowen_ZA
dc.subjectCameroonen_ZA
dc.subjectUCTD
dc.titleTrends in mortality and factors associated with mortality and morbidity amongst hospitalized low birth weigth infants at a tertiary level hospital in Cameroon, 2001-2005en_ZA
dc.typeThesisen_ZA
dc.rights.holderStellenbosch University


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