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Now showing items 31-40 of 474
Elucidation of the substrates of mycosin 3, an essential protease of Mycobacterium tuberculosis
(Stellenbosch : University of Stellenbosch, 2011-03)
ENGLISH ABSTRACT: Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), infects one third of the
world’s population and kills 1.7 million people per year. The increasing prevalence of multi- and
extensively ...
Analysis of hereditary haemochromatosis and clinical correlations in the elderly
(Stellenbosch : Stellenbosch University, 2000-12)
ENGLISH ABSTRACT: Hereditary haemochromatosis (HH) is an autosomal recessive iron storage disease where
the accumulation of iron in parenchymal organs may lead to diabetes, heart failure, liver
cirrhosis, arthropathy, ...
An investigation into the role of collectins in tuberculosis infection
(Stellenbosch : Stellenbosch University, 2005-03)
ENGLISH ABSTRACT:
Please see fulltext for abstract.
The relevance of apoptosis in the pathogenesis of human immunodeficiency virus-1 disease
(Stellenbosch : Stellenbosch University, 2004-12)
ENGLISH ABSTRACT: A simple and rapid scatter-based flow cytometric assay was developed to detect
apoptosis in CD4+ and CD8+ T cells from a mixed population of cells. The assay was
suitable for children.
Apoptotic PBMCs ...
The effect of an in utero high fat diet on the expression of transcription factors and glucose sensing in the developing rat pancreas
(Stellenbosch : Stellenbosch University, 2005-12)
ENGLISH ABSTRACT: A high fat diet (HFD) reduces beta-cell mass, impairs glucose signalling and is
involved in the development of Type 2 diabetes. Malnutrition during gestation is
hypothesized to irreversibly damage ...
A histological and morphometric assessment of endocrine and ductular proliferation in the adult rat pancreas using an occlusive pancreatic duct ligation model
(Stellenbosch : Stellenbosch University, 2000-03)
ENGLISH ABSTRACT: Diabetes Mellitus (DM) is synonymous with "B-cell failure". Ligation of the pancreatic
duct distally to its confluence into the bile duct has been shown to induce endocrine
tissue regeneration from a ...
The role of melatonin in cardioprotection : an investigation into the mechanisms involved in glucose homeostasis, microvascular endothelial function and mitochondrial function in normal and insulin resistant states
(Stellenbosch : Stellenbosch University, 2014-04)
ENGLISH ABSTRACT: Introduction:
The cardioprotective actions of the hormone melatonin against myocardial ischaemiareperfusion
injury (IRI) are well-established. It has recently been shown to prevent the harmful
effects ...
Investigation into the intracellular mechanisms whereby long-chain fatty acids protect the heart in ischaemia/reperfusion
(Stellenbosch : Stellenbosch University, 2005-03)
ENGLISH ABSTRACT: Although there is evidence for a protective role of long-chain polyunsaturated
fatty acids (PUFAs) in cardiovascular disease, their mechanism of action as
well as their participation in intracellular ...
Molecular genetic analysis of the neurokinin B (TAC3) and neurokinin B receptor (TAC3) genes as candidates for pre-eclampsia
(Stellenbosch : Stellenbosch University, 2004-12)
ENGLISH ABSTRACT: Hypertensive conditions of pregnancy, such as pre-eclampsia, are the principal direct
cause of maternal morbidity and mortality and affect up to 10% of first pregnancies
worldwide. The placenta is vital ...
Violence against women : impact on reproductive health and pregnancy outcome
(Stellenbosch : Stellenbosch University, 2003-03)
ENGLISH ABSTRACT: Introduction
Worldwide, up to 25% of women are assaulted during pregnancy, with estimates
varying between populations. Violence has been associated with adverse
pregnancy outcome, including preterm ...