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Value of different staging systems for predicting neurological outcome in childhood tuberculous meningitis

Van Toorn R.; Springer P.; Laubscher J.A.; Schoeman J.F. (2012)

BACKGROUND: The stage of tuberculous meningitis (TBM) at presentation is strongly associated with prognosis. OBJECTIVE: To compare different staging systems for TBM in predicting outcome. METHODS: The associations of ...

GCH1 in early-onset Parkinson's disease

Cobb, S. A.; Wider, C.; Ross, O. A.; Mata, I. F.; Adler, C. H.; Rajput, A.; Rajput, A. H.; Wu, R. M.; Hauser, R.; Josephs, K. A.; Carr, J.; Gwinn, K.; Heckman, M. G.; Aasly, J. O.; Lynch, T.; Uitti, R. J.; Wszolek, Z. K.; Kapatos, G.; Farrer, M. J. (2009)

Mutations in GTP-cyclohydrolase 1 (GCH1) cause autosomal dominant dopa-responsive dystonia (DRD), characterized by childhood-onset foot dystonia that later generalizes. DRD patients frequently present with associated ...

Nutritional status, quality of life and CD4 cell count of adults living with HIV/AIDS in the Ga-Rankuwa area (South Africa)

Venter M.E.; Gericke G.J.; Bekker P.J. (2009)

Objective: To determine if there was a relationship between CD4 cell count, nutritional status and self-reported quality of life (QoL) in HIV-infected adults. Design: Descriptive study in the quantitative research domain. ...

Analysis for a limited number of gene codons can predict drug resistance of Mycobacterium tuberculosis in a high-incidence community

Van Rie A.; Warren R.; Mshanga I.; Jordaan A.M.; Van Der Spuy G.D.; Richardson M.; Simpson J.; Gie R.P.; Enarson D.A.; Beyers N.; Van Helden P.D.; Victor T.C. (2001)

Correct and rapid diagnosis is essential in the management of multidrug-resistant tuberculosis (MDR-TB). In this population-based study of 61 patients with drug-resistant tuberculosis, we evaluated the frequency of mutations ...

Calculation of the stability of the IS6110 banding pattern in patients with persistent Mycobacterium tuberculosis disease

Warren R.M.; Van der Spuy G.D.; Richardson M.; Beyers N.; Borgdorff M.W.; Behr M.A.; Van Helden P.D. (2002)

The interpretation of molecular epidemiologic data of Mycobacterium tuberculosis infection is dependent on the understanding of the stability and evolutionary characteristics of the DNA fingerprinting marker used to classify ...

Evolution of the IS6110-based restriction fragment length polymorphism pattern during the transmission of Mycobacterium tuberculosis

Warren R.M.; Van der Spuy G.D.; Richardson M.; Beyers N.; Booysen C.; Behr M.A.; Van Helden P.D. (2002)

Interpretation of the molecular epidemiological data of Mycobacterium tuberculosis is dependent on the validity of the assumptions that have been made. It is assumed that the IS6110 banding pattern is sufficiently stable ...

The hypoosmotic swelling test in the Andrology Laboratory

Coetzee K.; De Villiers A.; Conradie E.; Menkveld R.; Kruger T.F.; Lombard C.J. (1990)

[No abstract available]

Improvement in mycobacterial yield and reduced time to detection in pediatric samples by use of a nutrient broth growth supplement

Brittle W.; Marais B.J.; Hesseling A.C.; Schaaf H.S.; Kidd M.; Wasserman E.; Botha T. (2009)

There is an urgent need to improve the methods used for the bacteriological diagnosis of childhood mycobacterial disease. This study compared the mycobacterial yields and the times to detection (in days) of mycobacteria ...

Outcome of children treated for cancer in the republic of Namibia

Wessels G.; Hesseling P.B. (1996)

The data of a survey undertaken to record all cases of childhood cancer in Namibia from 1983 to 1988 were analyzed to estimate 5-year survival rates. The projected survival rate for 150 children with cancer was 37% with ...

Headaches in patients with systemic lupus erythematosus: A comparative study

Whitelaw D.A.; Hugo F.; Spangenberg J.J.; Rickman R. (2004)

The incidence and nature of headaches in 85 systemic lupus erythematosus (SLE) patients attending an outpatient clinic were studied and compared to those experienced by 61 nurses. The two groups were similar in age, sex ...

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