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The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for children at 18 months

Duley, L.; Farrell, B.; Armstrong, N.; Spark, P.; Roberts, B.; Smyth, R.; Tivnan, M.; Laws, A.; Corfield, N.; Salte, A.; Thorn, L.; Altman, D.; Yu, L. M.; Abalos, E.; Carroli, B.; Dellepiane, L.; Duarte, M.; Fernandez, H.; Giordano, D.; Clarke, M.; Gray, A.; Hey, E.; Neilson, J.; Simon, J.; Doyle, L.; Kelly, T.; Squires, J.; Collins, R.; Karaoglou, A.; Lilford, R.; Moodley, J.; Robson, S.; Roberts, I.; Rubin, P.; Thornton J.; Twaddle, S.; Villar, J.; Walker, I.; Watkins, C.; Bimbashi, A.; Demalia, E.; Gliozheni ,O.; Shpata, A.; Karolinski, A.; Lamas, M.; Pesaresi, M.; Wainer, V.; Barbato, W.; Paciocco, M.; Bertin, M.; Boiza, E.; Castaldi, J.; Partida, Y.; Arias, C.; Farri, M.; Kerz, G.; Aguirre, J.; De Sagastizabal, M.; Falcone, R.; Morales, E.; Carroli, G.; Krupitzky, S.; Lopez, S.; Palermo, M.; Montes, Varela D.; Delprato, H.; Camusso, H.; Curioni, M.; Ludmer, E.; Brandi, R.; Martin, R.; Mesas, W.; Taralli, R.; Lezaola, M.; Morosini, M.; Andina, E.; Bernal, L.; Estiu, M.; Ulens, E.; Ortiz De Speranza, B.; Peyrano, A.; Damiano, M.; Saumench, C.; Horn, J.; Pritchard, M.; Smith-Orr, V.; Wilson, M.; Lawrence, A.; Watson, D.; Crowther, C.; Paynter, J.; Ashrafunnessa,; Mannan, M.; Shahidullah, M.; Shamsuddin, L.; Barros, Santos C.; Freire, S.; Melo, E.; Cobo, E.; Jaramillo, E.; Cardozo, C.; Fandino, N.; Gaitan, H.; Montano, L.; Lozano, J.; Rojas, M.; Breto, Garcia A.; Fuentes, Ramirez A.; Garcia, Miras R.; Sampera, S.; Farnot, U.; Gomez, E.; Rojas, G.; Valdes, R.; Abd El-Kreem, H.; Al-Hussaini, T.; Hammad, E.; Danso, K.; Kwapong, E.; Ofosu-Barko, E.; Padmini, Jasper M.; Peedicayil, A.; Regi, A.; Sharma, R.; Chauhan, A.; Raut, V.; Udani, R.; Batra, S.; Muthal-Rathore, A.; Ramji, S.; Zutshi, V.; Balakrishnan, S.; Eapen, E.; Koshy, G.; Ambardar, N.; Vadakkepat, P.; Vaidya, D.; Lema, V.; Rijken, Y.; Tadesse, E.; Dada, O.; Sofekun, A.; Ohiaeri, C.; Runsewe-Abiodun, T.; Adewole, I.; Adeyemo, A.; Brown, B.; Oladokun, R.; Adewale, O.; Inimgba, N.; John, C.; Ogu, R.; Ekele, B.; Isah, A.; Onankpa, B.; Jamelle, R.; Junejo, D.; Ruby, Faiz N.; Gul, F.; Sherin, A.; Bangash, K.; Mahmud, G.; Masud, K.; Tasneem, N.; Gassama, S.; Soyei, A.; Agarwal, P.; Rajadurai, V.; Pirani, N.; Delport, S.; Macdonald, P.; Mokhondo, R.; Pattinson, R.; Zondo, M.; Adhikari, M.; Mnguni, N.; Moodley, J.; Carstens, M.; Kirsten, G.; Steyn, W.; Van Zyl, J.; Helwig, A.; Jacobson, S. L.; Panosche, R.; Hammond, E.; Masanganise, L. (2007)

Objective: To assess the long-term effects of in utero exposure to magnesium sulphate for children whose mothers had pre-eclampsia. Design: Assessment at 18 months of age for children whose mothers were recruited to the ...

Triple therapy with clarithromycin, omeprazole, and amoxicillin for eradication of Helicobacter pylori in duodenal ulcer patients in Asia and Africa

Wong, B. C. Y.; Chang, F. Y.; Abid, S.; Abbas, Z.; Lin, B. R.; Van Rensburg, C.; Chen, P. C.; Schneider, H.; Simjee, A. E.; Hamid, S. S.; Seebaran, A.; Zhang, J.; Destefano, M.; Lam, S. K. (2000)

Background: Studies assessing the efficacy of triple therapy containing clarithromycin and amoxicillin for the eradication of Helicobacter pylori infection and healing of duodenal ulcers in Asian and African countries are ...

GCH1 in early-onset Parkinson's disease

Cobb, S. A.; Wider, C.; Ross, O. A.; Mata, I. F.; Adler, C. H.; Rajput, A.; Rajput, A. H.; Wu, R. M.; Hauser, R.; Josephs, K. A.; Carr, J.; Gwinn, K.; Heckman, M. G.; Aasly, J. O.; Lynch, T.; Uitti, R. J.; Wszolek, Z. K.; Kapatos, G.; Farrer, M. J. (2009)

Mutations in GTP-cyclohydrolase 1 (GCH1) cause autosomal dominant dopa-responsive dystonia (DRD), characterized by childhood-onset foot dystonia that later generalizes. DRD patients frequently present with associated ...

Analysis for a limited number of gene codons can predict drug resistance of Mycobacterium tuberculosis in a high-incidence community

Van Rie A.; Warren R.; Mshanga I.; Jordaan A.M.; Van Der Spuy G.D.; Richardson M.; Simpson J.; Gie R.P.; Enarson D.A.; Beyers N.; Van Helden P.D.; Victor T.C. (2001)

Correct and rapid diagnosis is essential in the management of multidrug-resistant tuberculosis (MDR-TB). In this population-based study of 61 patients with drug-resistant tuberculosis, we evaluated the frequency of mutations ...

Calculation of the stability of the IS6110 banding pattern in patients with persistent Mycobacterium tuberculosis disease

Warren R.M.; Van der Spuy G.D.; Richardson M.; Beyers N.; Borgdorff M.W.; Behr M.A.; Van Helden P.D. (2002)

The interpretation of molecular epidemiologic data of Mycobacterium tuberculosis infection is dependent on the understanding of the stability and evolutionary characteristics of the DNA fingerprinting marker used to classify ...

Evolution of the IS6110-based restriction fragment length polymorphism pattern during the transmission of Mycobacterium tuberculosis

Warren R.M.; Van der Spuy G.D.; Richardson M.; Beyers N.; Booysen C.; Behr M.A.; Van Helden P.D. (2002)

Interpretation of the molecular epidemiological data of Mycobacterium tuberculosis is dependent on the validity of the assumptions that have been made. It is assumed that the IS6110 banding pattern is sufficiently stable ...

Improvement in mycobacterial yield and reduced time to detection in pediatric samples by use of a nutrient broth growth supplement

Brittle W.; Marais B.J.; Hesseling A.C.; Schaaf H.S.; Kidd M.; Wasserman E.; Botha T. (2009)

There is an urgent need to improve the methods used for the bacteriological diagnosis of childhood mycobacterial disease. This study compared the mycobacterial yields and the times to detection (in days) of mycobacteria ...

Outcome of children treated for cancer in the republic of Namibia

Wessels G.; Hesseling P.B. (1996)

The data of a survey undertaken to record all cases of childhood cancer in Namibia from 1983 to 1988 were analyzed to estimate 5-year survival rates. The projected survival rate for 150 children with cancer was 37% with ...

An investigation in the possible effect of chronic headache on neuropsychological function in aCL-negative patients with SLE

Whitelaw D.A.; Spangenberg J.J. (2009)

exists as to whether patients with migraine may suffer cortical damage. We investigate the possible association between impaired cognitive function and chronic headache in lupus patients. Sixty one patients with systemic ...

Headaches in patients with systemic lupus erythematosus: A comparative study

Whitelaw D.A.; Hugo F.; Spangenberg J.J.; Rickman R. (2004)

The incidence and nature of headaches in 85 systemic lupus erythematosus (SLE) patients attending an outpatient clinic were studied and compared to those experienced by 61 nurses. The two groups were similar in age, sex ...

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