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Improvement in mycobacterial yield and reduced time to detection in pediatric samples by use of a nutrient broth growth supplement
(2009)
There is an urgent need to improve the methods used for the bacteriological diagnosis of childhood mycobacterial disease. This study compared the mycobacterial yields and the times to detection (in days) of mycobacteria ...
Diagnosing mycobacterial lymphadenitis in children using fine needle aspiration biopsy: Cytomorphology, ZN staining and autofluorescence-making more of less
(2008)
Although the incidence of TB has stabilized or declined in most world regions, it is increasing in Africa, Southeast Asia, and the Eastern Mediterranean, fuelled by the HIV pandemic. More than 4,000 people died daily from ...
Sonographic diagnosis of biliary ascariasis
(1982)
In a prospective 6 month study, sonographic diagnosis of biliary ascariasis was made in 12 patients: In five, the diagnosis was confirmed by other means, mainly intravenous cholangiography. In three, such confirmation was ...
Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa
(2010)
Background: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in children retained in care and in all ...
Virologic failure and second-line antiretroviral therapy in children in South Africa-the IeDEA Southern Africa collaboration
(2011)
Background: With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determinants of virologic ...
Hepatic toxicity during chemotherapy for severe tuberculous meningitis
(1987)
The possible development of hepatotoxic effects as a result of high dosages of isoniazid, rifampin, pyrazinamide, and ethionamide was assessed in 56 young children (median age, 22 months) treated for severe tuberculous ...
Combined use of pleural adenosine deaminase with lymphocyte/neutrophil ratio: Increased specificity for the diagnosis of tuberculous pleuritis
(1996)
Increased pleural fluid adenosine deaminase (ADA) activity is classically associated with tuberculous pleuritis. However, increased activity can also occur in a number of other diseases and this may negatively affect the ...
Mutations of the light meromyosin domain of the β-myosin heavy chain rod in hypertrophic cardiomyopathy
(2002)
Familial hypertrophic cardiomyopathy (HCM) is caused by mutations in 9 sarcomeric protein genes. The most commonly affected is β-myosin heavy chain (MYH7), where missense mutations cluster in the head and neck regions and ...
Can CT predict the level of CSF block in tuberculous hydrocephalus?
(2004)
Introduction: Treatment of obstructive hydrocephalus in children with tuberculous meningitis (TBM) depends on the level of the cerebrospinal fluid (CSF) block. Air-encephalography is regarded as the gold standard for ...
Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid
(2010)
Aim: Little is known about pyridoxine nutriture of children treated with isoniazid (INH) regimens. This study documents plasma pyridoxal 5′-phosphate (PLP) concentrations in children, HIV-infected and HIV-uninfected, ...