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Analysis for a limited number of gene codons can predict drug resistance of Mycobacterium tuberculosis in a high-incidence community
(2001)
Correct and rapid diagnosis is essential in the management of multidrug-resistant tuberculosis (MDR-TB). In this population-based study of 61 patients with drug-resistant tuberculosis, we evaluated the frequency of mutations ...
Childhood drug-resistant tuberculosis in the Western Cape Province of South Africa
(2006)
Aim: Continued surveillance of drug resistance amongst children presenting with culture-confirmed tuberculosis to a tertiary care hospital and to community clinics. Methods: Drug susceptibility testing for isoniazid and ...
The 5-year outcome of multidrug resistant tuberculosis patients in the Cape Province of South Africa
(1996)
Little is known about the outcome of multidrug resistant (MDR) tuberculosis (TB) in developing countries. In this study, 443 patients with MDR-TB, defined as resistance to two Or more antituberculosis drugs, were identified ...
Pulmonary tuberculosis in children with rheumatic carditis
(1998)
Rheumatic carditis is the commonest acquired heart lesion in children in South Africa, and tuberculosis is one of the major health problems in the Western Cape. This study determined that children with rheumatic fever have ...
Risk of pulmonary tuberculosis in children with congenital heart disease
(1995)
Children with low-flow congenital heart lesions are reported to have an increased incidence of pulmonary tuberculosis. The aim of this study was to investigate if children with congenital heart disease have an increased ...
Management of children with tuberculosis admitted to a pediatric intensive care unit
(1998)
Objectives. To review the incidence, clinical features, ventilatory support and outcome of children with tuberculosis (TB) admitted to a Pediatric Intensive Care Unit (PICU) in a region with an high incidence of TB. Materials ...
Classification of drug-resistant tuberculosis in an epidemic area
(2000)
Background: Traditionally, patients with drug-resistant tuberculosis are classified as having acquired drug-resistant or primary drug-resistant disease on the basis of a history of previous tuberculosis treatment. Only ...
Evaluation of young children in household contact with adult multidrug- resistant pulmonary tuberculosis cases
(1999)
Background. The prevention and management of multidrug-resistant (MDR) tuberculosis has received much attention, but little attention has been given to children with MDR tuberculosis or children in contact with adults with ...
Radiographic signs and symptoms in children treated for tuberculosis: Possible implications for symptom-based screening in resource-limited settings
(2006)
Background: The World Health Organization advises active tracing of children younger than 5 years old in household contact with a sputum smear-positive tuberculosis index case. This study compared radiographic disease ...