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The use of adenosine deaminase and interferon-γ as diagnostic tools for tuberculous pericarditis
(2002)
Background: Traditional diagnostic tests for pericardial tuberculosis (TB) are insensitive and often require long culture periods, and this has led to more emphasis being placed on biochemical tests such as the pericardial ...
Role of biochemical tests in the diagnosis of large pericardial effusions
(2002)
Study objectives: To determine the biochemical characteristics of large pericardial effusions in various disease states, and to assess their utility as diagnostic tools. Setting: An academic university hospital in the ...
Combined use of pleural adenosine deaminase with lymphocyte/neutrophil ratio: Increased specificity for the diagnosis of tuberculous pleuritis
(1996)
Increased pleural fluid adenosine deaminase (ADA) activity is classically associated with tuberculous pleuritis. However, increased activity can also occur in a number of other diseases and this may negatively affect the ...
The diagnostic utility of adenosine deaminase isoenzymes in tuberculous pleural effusions
(2009)
SETTING: Pleural adenosine deaminase (ADA) levels have been found to be useful in diagnosing tuberculous pleuritis. Elevated ADA levels have been attributed to ADA2 isoenzyme, although no comprehensive studies have evaluated ...
The role of histopathology in establishing the diagnosis of tuberculous pericardial effusions in the presence of HIV
(2006)
Aims: To establish the influence of human immunodeficiency virus (HIV) infection on the histopathological features of patients presenting with tuberculous pericarditis. Methods and results: A prospective study was carried ...
Use of adenosine deaminase as a diagnostic tool for tuberculous pleurisy
(1995)
Background - A statistical audit of adenosine deaminase (ADA) in pleural effusions was undertaken. Methods - ADA analysis, cytological and microbiological examinations, and differential cell counts were performed on 462 ...
Isoenzymes of adenosine deaminase in pleural effusions: A diagnostic tool?
(1998)
SETTING: Tygerberg Hospital, an academic teaching hospital, Republic of South Africa. OBJECTIVE: To identify the adenosine deaminase (ADA) isoenzymes as a diagnostic tool for tuberculosis in pleural effusions with increased ...
A randomized, placebo-controlled, double-blind phase 2 study of docetaxel compared to docetaxel plus zosuquidar (LY335979) in women with metastatic or locally recurrent breast cancer who have received one prior chemotherapy regimen
(2009)
Purpose: To determine if concomitant administration of docetaxel plus zosuquidar.3HC1 can prolong progression-free survival in patients with metastatic breast cancer. Methods: A randomized, double-blind, multicenter, ...
The management of tuberculous pericardial effusion: Experience in 233 consecutive patients
(2007)
Aim: We report on the 30-day and one-year outcome of consecutive effusive pericarditis patients, including those with tuberculous pericarditis, over a six-year-period. Methods and Results: Patients with large pericardial ...
Patients' motivations for participating in cardiovascular clinical trials: A local perspective
(2009)
Objective: To investigate patients' motivations for participating in cardiovascular clinical trials. Methods: Patients attending TREAD Research, located within Tygerberg Hospital, Parow, Western Cape, between January 2005 ...