Search

Now showing items 1-5 of 5

The role of melatonin in cardioprotection : an investigation into the mechanisms involved in glucose homeostasis, microvascular endothelial function and mitochondrial function in normal and insulin resistant states

Nduhirabandi, Frederic (Stellenbosch : Stellenbosch University, 2014-04)

ENGLISH ABSTRACT: Introduction: The cardioprotective actions of the hormone melatonin against myocardial ischaemiareperfusion injury (IRI) are well-established. It has recently been shown to prevent the harmful effects ...

Measurement of free radicals and their effects on human spermatozoa

Lampiao, Fanuel (Stellenbosch : University of Stellenbosch, 2006-03)

In this study, we presented data on the role of free radicals in human spermatozoa, particularly in the context of centrifugation and the potential development of defective sperm function. In order to achieve this, methods ...

Exposure of cardiac microvascular endothelial cells to harmful stimuli : a study of the cellular responses and mechanisms

Genis, Amanda (Stellenbosch : Stellenbosch University, 2014-04)

ENGLISH ABSTRACT: Exposure to harmful stimuli can render vascular endothelial cells dysfunctional, characterised by reduced nitric oxide (NO) bioavailibility. Endothelial dysfunction (ED) is a reversible precursor ...

Endothelial dysfunction in cardiac microvascular endothelial cells : an investigation into cellular mechanisms and putative role of oleanolic acid in reversing endothelial dysfunction

Mudau, Mashudu (Stellenbosch : University of Stellenbosch, 2010-12)

ENGLISH ABSTRACT: Introduction: The discovery of the endothelium as a regulator of vascular tone, and the subsequent discovery of nitric oxide (NO) as the major endothelium-derived relaxing factor (EDRF), has opened up ...

A diffusion tensor imaging study in HIV patients with and without apathy

Fouche, Jean-Paul (Stellenbosch : University of Stellenbosch, 2010-12)

ENGLISH ABSTRACT: HIV/AIDS is a global epidemic that accounts for a large percentage of the mortality in South Africa every year. Since the implementation of anti-retroviral treatment, HIV positive individuals have been ...