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Postconditioning the isolated perfused rat heart : the role of kinases and phosphatases
(Stellenbosch : Stellenbosch University, 2008-03)
ENGLISH ABSTRACT: It has recently been observed that the application of multiple short cycles of reperfusion and ischaemia, at the onset of reperfusion, elicits cardioprotection against injury due to prior sustained ...
Role of cyclic adenosine monophosphate (cAMP), cyclic guanosine monophosphate (cGMP) and p38 mitogen activated protein kinase (p38 MAPK) in preconditioning of the ischaemic myocardium
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: Ischaemic preconditioning (PC) is the phenomenon whereby a short episode of
coronary occlusion followed by reperfusion protects the myocardium against a
subsequent period of prolonged (also called index ...
Possible mechanisms for levosimendaninduced cardioprotection
(Stellenbosch : Stellenbosch University, 2008-12)
Background and purpose. To limit ischaemic injury, rapid restoration of coronary
blood flow is required, which will in turn reduce infarct size. However, reperfusion
itself causes myocyte death – a phenomenon termed ...