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The mycosins, a family of secreted subtilisin-like serine proteases associated with the immunologically-important ESAT-6 gene clusters of Mycobacterium tuberculosis
(Stellenbosch : Stellenbosch University, 2002-12)
ENGLISH ABSTRACT: Pathogenic organisms frequently utilize proteases to perform specific functions related to
virulence. There is little information regarding the role of proteolysis in Mycobacterium tuberculosis
and no ...
Immune regulation in children and adults in a community with a high incidence of tuberculosis
(Stellenbosch : Stellenbosch University, 1998-12)
ENGLISH ABSTRACT: There is a progressive maturation of the immune system from infancy to adulthood. The
immature immune system in early life is characterised by impaired macrophage function
and antigen presentation as ...
Immune responses in a community with a high incidence of tuberculosis
(Stellenbosch : Stellenbosch University, 2004-03)
ENGLISH ABSTRACT: It is estimated that about one third of the world's population is infected with
Mycobacterium tuberculosis (M. tuberculosis). Of those infected, only 10 % will develop
disease of which 3-5 % will relapse ...