Search
Now showing items 1-10 of 26
Pyrazinamide plasma concentrations in young children with tuberculosis
(2011)
Pyrazinamide plasma concentrations were determined in 34 children (median age, 3.32 years) 1 month after commencing antituberculosis treatment. The median (interquartile range) peak concentration was 30.7 (25.5, 35.0) mg/L ...
Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid
(2010)
Aim: Little is known about pyridoxine nutriture of children treated with isoniazid (INH) regimens. This study documents plasma pyridoxal 5′-phosphate (PLP) concentrations in children, HIV-infected and HIV-uninfected, ...
Cavitation of the Ghon focus in an HIV-infected infant who acquired tuberculosis after the initiation of HAART
(2009)
Tuberculosis immune reconstitution inflammatory syndrome (IRIS) may present as new or worsening cavitation. We present an HIV-infected infant in whom TB infection and subsequent cavitation of the Ghon focus appeared to ...
An HIV-infected infant with Bacille Calmette-Guérin disease, recurrent and multidrug-resistant tuberculosis complicated by acute cor pulmonale and hepatitis while on antiretroviral therapy
(2007)
We describe the management of an HIV-infected infant with multisystem disease. The infant presented with severe disease at 3 months of age. Initiation of antiretroviral therapy (ART) was delayed through initial lack of ...
The 5-year outcome of multidrug resistant tuberculosis patients in the Cape Province of South Africa
(1996)
Little is known about the outcome of multidrug resistant (MDR) tuberculosis (TB) in developing countries. In this study, 443 patients with MDR-TB, defined as resistance to two Or more antituberculosis drugs, were identified ...
HIV and childhood tuberculosis: The way forward
(2004)
Tuberculosis has been a major cause of morbidity and mortality in under-resourced communities. By causing progressive immunodeficiency, the human immunodeficiency virus (HIV) increases susceptibility to tuberculosis in an ...
Mycobacterium tuberculosis transmission is not related to household genotype in a setting of high endemicity
(2009)
Among the different strains of Mycobacterium tuberculosis, Beijing has been identified as an emerging genotype. Enhanced transmissibility provides a potential mechanism for genotype selection. This study evaluated whether ...
Tuberculosis in oncology patients
(2008)
Background: There is a dearth of studies addressing the incidence and clinical presentation of tuberculosis (TB) in children with cancer. Aim: To evaluate the incidence of TB in paediatric oncology patients at Tygerberg ...