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Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid
(2010)
Aim: Little is known about pyridoxine nutriture of children treated with isoniazid (INH) regimens. This study documents plasma pyridoxal 5′-phosphate (PLP) concentrations in children, HIV-infected and HIV-uninfected, ...
Isoniazid pharmacokinetics in children treated for respiratory tuberculosis
(2005)
Aims: To define the pharmacokinetics of isoniazid (INH) in children with tuberculosis in relation to the N-acetyltransferase 2 (NAT2) genotype. Methods: The first order elimination rate constant (k) and area under the ...
The association of age and elimination of isoniazid: An example of median regression with heteroscedasticity
(2003)
The rate of elimination of the tuberculosis drug INH(k) varies from person to person, is characteristic of certain genotypes and has been thought to be age dependent. The data in this paper are subjected to a regression ...