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Antiretroviral therapy adherence and drug-drug interactions in the aging HIV population

Nachega J.B. Hsu A.J. Uthman O.A. Spinewine A. Pham P.A. (2012)

It is estimated that by 2015 more than half of all HIV-infected individuals in the United States will be 50 years of age or older. As this population ages, the frequency of non-AIDS related comorbidities increases, which ...

Cross-cultural adaptation and validation of the self-reporting questionnaire among HIV+ individuals in a rural ART program in southern Uganda

Nakimuli-Mpungu E. Mojtabai R. Alexandre P.K. Katabira E. Musisi S. Nachega J.B. Bass J.K. (2012)

Background: HIV treatment programs are in need of brief, valid instruments to identify common mental disorders such as depression. Aim: To translate and culturally adapt the Self-Reporting Questionnaire (SRQ-20) for use ...

Depression, alcohol use and adherence to antiretroviral therapy in Sub-Saharan Africa : a systematic review

Nakimuli-Mpungu E. Bass J.K. Alexandre P. Mills E.J. Musisi S. Ram M. Katabira E. Nachega J.B. (2011)

This study evaluated estimates of depression symptoms, major depression, alcohol use or disorders and their association with ART adherence in sub-Saharan Africa. Studies published between January 1, 2006 and July 31, 2011 ...

Depression, Alcohol Use and Adherence to Antiretroviral Therapy in Sub-Saharan Africa: A Systematic Review

Nakimuli-Mpungu E. Bass J.K. Alexandre P. Mills E.J. Musisi S. Ram M. Katabira E. Nachega J.B. (2011)

Evaluation of paradoxical TB-associated IRIS with the use of standardized case definitions for resource-limited settings

Eshun-Wilson I. Havers F. Nachega J.B. Prozesky H.W. Taljaard J.J. Zeier M.D. Cotton M. Simon G. Soentjens P. (2010)

Objective: Standardized case definitions have recently been proposed by the International Network for the Study of HIV-associated immune reconstitution inflammatory syndrome (INSHI; [IRIS]) for use in resource-limited ...

Nachega J.B. Morroni C. Zuniga J.M. Sherer R. Beyrer C. Solomon S. Schechter M. Rockstroh J. (2012)

Background: Little is known globally about the perspectives of people living with HIV/AIDS (PLWHA) on perceived HIV-related stigma and its consequences. Methods: Cross-sectional study (January-March 2010) of perceived ...

HIV treatment adherence, drug resistance, virologic failure: Evolving concepts

Nachega J.B. Marconi V.C. van Zyl G.U. Gardner E.M. Preiser W. Hong S.Y. Mills E.J. Gross R. (2011)

Poor adherence to combined antiretroviral therapy (cART) has been shown to be a major determinant of virologic failure, emergence of drug resistant virus, disease progression, hospitalizations, mortality, and health care ...

HIV treatment adherence, patient health literacy, and health care provider-patient communication: Results from the 2010 AIDS Treatment for Life International Survey

Nachega J.B. Morroni C. Zuniga J.M. Schechter M. Rockstroh J. Solomon S. Sherer R. (2012)

Background: Little is known about patients' health literacy regarding antiretroviral therapy (ART) adherence and drug resistance and patient-provider communication about these topics. Design and Methods: The AIDS Treatment ...

Male gender predicts mortality in a large cohort of patients receiving antiretroviral therapy in Uganda

Mills E.J. Bakanda C. Birungi J. Chan K. Hogg R.S. Ford N. Nachega J.B. Cooper C.L. (2011)

Management of adult active tuberculosis disease in era of HIV pandemic, current practices and future perspectives

Nachega J.B. Rosenkranz B. Simon G. Chaisson R.E. Diacon A.H. Taljaard J. (2011)

The global impact of the HIV epidemic on the prevention and management of tuberculosis has resulted in added levels of complexity for physicians and other health- care workers caring for these patients. In addition to the ...

Management of adult active tuberculosis disease in era of HIV pandemic, current practices and future perspectives

Nachega J.B. Rosenkranz B. Simon G. Chaisson R.E. Diacon A.H. Taljaard J. (2011)

The global impact of the HIV epidemic on the prevention and management of tuberculosis has resulted in added levels of complexity for physicians and other health- care workers caring for these patients. In addition to the ...

Methodology matters : what type of research is suitable for evaluating community treatment supporters for HIV and tuberculosis treatment?

Maher D. Harries A.D. Nachega J.B. Jaffar S. (2012-02-22)

The choice of research method relevant to the evaluation of delivery of a health intervention is not always straightforward. We use the evaluation of HIV and tuberculosis community treatment supporters in promoting adherence ...

Methodology matters: What type of research is suitable for evaluating community treatment supporters for HIV and tuberculosis treatment?

Maher D. Harries A.D. Nachega J.B. Jaffar S. (2012-01-18)

he choice of research method relevant to the evaluation of delivery of a health intervention is not always straightforward. We use the evaluation of HIV and tuberculosis community treatment supporters in promoting adherence ...

Progression and persistence of low-grade cervical squamous intraepithelial lesions in women living with human immunodeficiency virus

Zeier M.D. Botha M.H. Van Der Merwe F.H. Eshun-Wilson I. Van Schalkwyk M. La Grange M. Mason D. Louw M. Nachega J.B. (2012)

Objective: This study aimed to investigate the progression and persistence of low-grade squamous intraepithelial lesions (SILs) in human immunodeficiency virus (HIV)-infected women. Methods: Study participants for this ...

Rise in rifampicin-monoresistant tuberculosis in Western Cape, South Africa

Mukinda F.K. Theron D. Van Der Spuy G.D. Jacobson K.R. Roscher M. Streicher E.M. Musekiwa A. Coetzee G.J. Victor T.C. Marais B.J. Nachega J.B. Warren R.M. Schaaf H.S. (2012)

SETTING: Brewelskloof Hospital, Western Cape, South Africa. OBJECTIVES: To verify the perceived increase in rifampicin monoresistant tuberculosis (RMR-TB) in the Cape Winelands-Overberg region and to identify potential ...

Survival of hiv-infected adolescents on antiretroviral therapy in uganda: Findings from a nationally representative cohort in uganda

Bakanda C. Birungi J. Mwesigwa R. Nachega J.B. Chan K. Palmer A. Ford N. Mills E.J. (2011)

Background: Adolescents have been identified as a high-risk group for poor adherence to and defaulting from combination antiretroviral therapy (cART) care. However, data on outcomes for adolescents on cART in resource-limited ...

Targeting HIV: Past, present and future

Zeier M.D. Nachega J.B. (2011)

Since the identification of the Human Immunodeficiency Virus (HIV) as the cause of the syndrome of Acquired Immunodeficiency Syndrome (AIDS), there has been an evolution of compounds targeting the replication of the virus ...

Targeting tuberculosis and HIV/AIDS: A global progress report of a deadly partnership

Nachega J.B. Rosenkranz B. (2011)

[No abstract available]

The global status of HIV drug resistance: Clinical and public-health approaches for detection, treatment and prevention

Hong S.Y. Nachega J.B. Kelley K. Bertagnolio S. Marconi V.C. Jordan M.R. (2011)

Antiretroviral therapy (ART) scale-up in resource limited settings (RLS) has been successful, utilizing a standardized population-based approach to ART delivery. An unintended consequence of treatment scale-up is the ...

Update on world health organization HIV drug resistance prevention and assessment strategy: 2004-2011

Jordan M.R. Bennett D.E. Wainberg M.A. Havlir D. Hammer S. Yang C. Morris L. Peeters M. Wensing A.M. Parkin N. Nachega J.B. Phillips A. De Luca A. Geng E. Calmy A. Raizes E. Sandstrom P. Archibald C.P. Perriens J. McClure C.M. Hong S.Y. McMahon J.H. Dedes N. Sutherland D. Bertagnolio S. (2012)

The HIV drug resistance (HIVDR) prevention and assessment strategy, developed by the World Health Organization (WHO) in partnership with HIVResNet, includes monitoring of HIVDR early warning indicators, surveys to assess ...

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